Radiation as an Immune Modulator: Where We Are With Modern Total Body Irradiation

E Simiele, S Dandapani, C Han, J Wong… - Seminars in Radiation …, 2025 - Elsevier
Total body irradiation (TBI) has been an important component of myeloablative and
nonmyeloablative conditioning regimens for allogeneic hematopoietic stem cell …

Optimised conformal total body irradiation: a heterogeneous practice, so where next?

S Misson-Yates, R Cunningham… - The British Journal of …, 2023 - academic.oup.com
The use of volumetric arc therapy and inverse planning has been in routine use in
radiotherapy for two decades. However, use in total body irradiation (TBI) has been more …

Volumetric modulated arc therapy for total body irradiation: A feasibility study using Pinnacle3 treatment planning system and Elekta Agility™ linac

K Symons, C Morrison, J Parry… - Journal of Applied …, 2018 - Wiley Online Library
A study was undertaken to explore the use of volumetric modulated arc therapy (VMAT) for
total body irradiation (TBI). Five patient plans were created in Pinnacle3 using nine 6 MV …

[HTML][HTML] Total body irradiation and total skin irradiation techniques in Belgium and the Netherlands: current clinical practice

PW Koken, LHP Murrer - Advances in radiation oncology, 2021 - Elsevier
Abstract Purpose In 2014, a Belgian/Dutch Nederlandse Commissie voor
Stralingsdosimetrie (NCS) task group was formed to develop guidelines on the clinical …

Extended SSD VMAT treatment for total body irradiation

G Pierce, A Balogh, R Frederick… - Journal of applied …, 2019 - Wiley Online Library
In this work, we develop a total body irradiation technique that utilizes arc delivery, a buildup
spoiler, and inverse optimized multileaf collimator (MLC) motion to shield organs at risk. The …

Total body irradiation in Australia and New Zealand: results of a practice survey

LS Fog, A Wirth, M MacManus, S Downes… - … Engineering Sciences in …, 2020 - Springer
Total body irradiation (TBI) is an important treatment modality for the preparation of patients
for bone marrow transplants. It is technically challenging and the actual delivery may vary …

Total Body Irradiation–Based Conditioning Regimen Improved the Survival of Adult Patients With T-Cell Lymphoblastic Lymphoma After Allogeneic Peripheral Blood …

J Niu, Z Chen, J Gao, H Qiu, L Wan… - Cell …, 2022 - journals.sagepub.com
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is one of the consolidation
modalities for adult patients with T-cell lymphoblastic lymphoma (T-LBL). However, the …

Dose to organs at risk for total body irradiation: Single‐institution data using the modulated arc total body irradiation technique

B Effeney, A Pullar, J Burbery… - Pediatric Blood & …, 2024 - Wiley Online Library
Background Organs at risk (OAR) dose reporting for total body irradiation (TBI) patients is
limited, and standardly reported only as mean doses to the lungs and kidneys …

[HTML][HTML] Large-field irradiation techniques in Germany: A DGMP Working Group survey on the current clinical implementation of total body irradiation, total skin …

L Heuchel, S Garbe, A Lühr, M Shariff - Zeitschrift für Medizinische Physik, 2024 - Elsevier
In 2023, a Germany-wide survey on the current clinical practice of three different large field
irradiation techniques (LFIT), namely total body irradiation (TBI), total skin irradiation (TSI) …

Molecular modeling and implications of Biochanin A on ghrelin and IGF-1/myostatin signaling in radiation triggered cachexia

A Shaheen, HA Gheita, HM Karam, NH Zaher… - Future Journal of …, 2024 - Springer
Background Cachexia, a loss of appetite and body weight as a result of systemic
inflammation, considered one of the unavoidable side effects of radiation therapy …