Sweat analysis by means of minimally invasive wearable sensors is considered a potentially
disruptive method for assessing clinical parameters, with exciting applications in early …

Abstract NLRP3/IL-1β activation via thioredoxin (TRX)/thioredoxin-interacting protein
(TXNIP) following mitochondria ROS (mtROS) overproduction plays a key role in …

The connection between inflammation and cancer was initially recognized by Rudolf
Virchow in the nineteenth century. During the last decades, a large body of evidence has …

Background Helicobacter pylori-induced peptic ulceration is less likely to occur in patients
with a strong gastric anti-inflammatory regulatory T cell (Treg) response. Migration of Tregs …

The mechanisms underlying rapid elimination of herpes simplex virus-2 (HSV-2) in the
human genital tract despite low CD8+ and CD4+ tissue-resident T cell (Trm cell) density are …

The formulation of next-generation probiotics requires competent preclinical studies to show
their efficacy and safety status. This study aims to confirm the safety of the prolonged oral …

Simple Summary The present study of blood chemical, cytokine and hormone indicators in
male and female pigs offered insights into the combined effects of maternal immune …

A deeper pathophysiologic understanding of available mouse models of sickle cell disease
(SCD), such as the Townes model, will help improve preclinical studies. We evaluated …

Protein biomarkers, especially cytokines, play a pivotal role in the diagnosis and treatment of
a wide spectrum of diseases. Therefore, a critical need for advanced cytokine sensors has …

Abstract Background: Chronic infection with Helicobacter pylori leads to gastritis and in a
subpopulation of infected individuals to ulcers and cancer. Bacterial virulence factors and …