Identification of RNA structures and their roles in RNA functions
The development of high-throughput RNA structure profiling methods in the past decade has
greatly facilitated our ability to map and characterize different aspects of RNA structures …
greatly facilitated our ability to map and characterize different aspects of RNA structures …
Translational regulation by uORFs and start codon selection stringency
In addition to the main, protein-coding, open reading frame (mORF), many eukaryotic
mRNAs contain upstream ORFs (uORFs) initiated at AUG or near-cognate codons residing …
mRNAs contain upstream ORFs (uORFs) initiated at AUG or near-cognate codons residing …
[HTML][HTML] Pervasive downstream RNA hairpins dynamically dictate start-codon selection
Translational reprogramming allows organisms to adapt to changing conditions. Upstream
start codons (uAUGs), which are prevalently present in mRNAs, have crucial roles in …
start codons (uAUGs), which are prevalently present in mRNAs, have crucial roles in …
Folding the mitochondrial UPR into the integrated stress response
NS Anderson, CM Haynes - Trends in cell biology, 2020 - cell.com
Eukaryotic cells must accurately monitor the integrity of the mitochondrial network to
overcome environmental insults and respond to physiological cues. The mitochondrial …
overcome environmental insults and respond to physiological cues. The mitochondrial …
A high-resolution temporal atlas of the SARS-CoV-2 translatome and transcriptome
COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
which infected> 200 million people resulting in> 4 million deaths. However, temporal …
which infected> 200 million people resulting in> 4 million deaths. However, temporal …
Natural uORF variation in plants
J Wang, J Liu, Z Guo - Trends in Plant Science, 2024 - cell.com
Taking advantage of natural variation promotes our understanding of phenotypic diversity
and trait evolution, ultimately accelerating plant breeding, in which the identification of …
and trait evolution, ultimately accelerating plant breeding, in which the identification of …
A natural uORF variant confers phosphorus acquisition diversity in soybean
Z Guo, H Cao, J Zhao, S Bai, W Peng, J Li… - Nature …, 2022 - nature.com
Phosphorus (P) is an essential element for all organisms. Because P fertilizers are a non-
renewable resource and high fixation in soils, sustainable agriculture requires researchers …
renewable resource and high fixation in soils, sustainable agriculture requires researchers …
Protein synthesis control in cancer: selectivity and therapeutic targeting
Translational control of mRNAs is a point of convergence for many oncogenic signals
through which cancer cells tune protein expression in tumorigenesis. Cancer cells rely on …
through which cancer cells tune protein expression in tumorigenesis. Cancer cells rely on …
Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
Proteogenomic identification of translated small open reading frames has revealed
thousands of previously unannotated, largely uncharacterized microproteins, or …
thousands of previously unannotated, largely uncharacterized microproteins, or …