Interferon-λs: the modulators of antivirus, antitumor, and immune responses

M Li, X Liu, Y Zhou, SB Su - Journal of leukocyte biology, 2009 - academic.oup.com
Recent findings concerning the biology of IFN-λs and their pathophysiological roles in viral
infection, cancer, and immune responses of the innate and adaptive arms are summarized …

Challenges and opportunities in the purification of recombinant tagged proteins

AS Pina, CR Lowe, ACA Roque - Biotechnology advances, 2014 - Elsevier
The purification of recombinant proteins by affinity chromatography is one of the most
efficient strategies due to the high recovery yields and purity achieved. However, this is …

Phenylalanine biosynthesis in Arabidopsis thaliana: identification and characterization of arogenate dehydratases

MH Cho, ORA Corea, H Yang, DL Bedgar… - Journal of Biological …, 2007 - ASBMB
There is much uncertainty as to whether plants use arogenate, phenylpyruvate, or both as
obligatory intermediates in Phe biosynthesis, an essential dietary amino acid for humans …

Cloning and expression of an anti-cancerous cytokine: human IL-29 gene in Chlamydomonas reinhardtii

M Akram, MA Khan, N Ahmed, R Bhatti, R Pervaiz… - AMB Express, 2023 - Springer
Green algae, Chlamydomonas reinhardtii, with low cultivation cost, absence of endotoxins
and insusceptibility to human pathogens is emerging as a potential system for the future …

[PDF][PDF] Роль цитокинов в иммунологической функции кожи

ОВ Белова, ВЯ Арион… - Иммунопатология …, 2008 - researchgate.net
Аннотация В статье представлены данные по цитокиновой регуля ции в коже. Описаны
структура и биологические эффек ты основных цитокинов, связанных с кожей …

Enhanced soluble expression of active recombinant human interleukin-29 using champion pET SUMO system

A Munir, N Ahmed, M Akram, NA Fujimura, S Tahir… - Biotechnology …, 2023 - Springer
Current research focuses on the soluble and high-level expression of biologically active
recombinant human IL-29 protein in Escherichia coli. The codon-optimized IL-29 gene was …

An extraovarian aspartic protease accumulated in tick oocytes with vitellin-degradation activity

PC Pohl, MHF Sorgine, AT Leal, C Logullo… - … and Physiology Part B …, 2008 - Elsevier
An aspartic endopeptidase named THAP, from the eggs of the tick Riphicephalus
(Boophilus) microplus, has been suggested to be involved in vitellin-degradation. Here we …

On-column refolding purification and characterization of recombinant human interferon-λ1 produced in Escherichia coli

M Li, D Huang - Protein Expression and Purification, 2007 - Elsevier
Interferon-lambda1 (IFN-λ1) is a member of the recently discovered type III IFNs (IFN-λ),
which possesses antiviral, antitumor, and immunomodulatory activities. In this study, the …

Clean and folded: production of active, high quality recombinant human interferon-λ1

A Shaldzhyan, Y Zabrodskaya, N Yolshin, T Kudling… - Process …, 2021 - Elsevier
Type III interferons exhibit antiviral activity against influenza viruses, coronaviruses,
rotaviruses, and others. In addition, this type of interferon theoretically has therapeutic …

High-level expression and one-step purification of a soluble recombinant human interleukin-37b in Escherichia coli

J Gu, X Gao, X Pan, X Peng, Y Li, M Li - Protein expression and purification, 2015 - Elsevier
Abstract Interleukin (IL)-37 is a novel member of the IL-1 cytokine family. However, as a
result of lacking efficient method to generate relatively large quantity of IL-37, little is known …