A tandem addition/cyclization reaction between trifluoromethyl N-acylhydrazones and
cyanamide is described, which provides a novel and efficient process for the synthesis of …

Trifluoromethyl group (CF 3) is a privilege scaffold in fluorine-containing drugs,
agrochemicals and material science. Hence, the development of highly efficient methods for …

An efficient and practical protocol for the preparation of trifluoromethylpyrrolopyrazole
derivatives were developed from the [3+ 2] cycloaddition reaction of readily available …

Nitrogen-containing organofluorine derivatives, which are prepared using fluorinated
building blocks, are among the most important active fragments in various pharmaceutical …

As novel difluoromethyl building blocks, difluoromethylated N-acylhydrazones react with
allyltrimethylsilanes and the halogen source via a tandem addition/cyclization/halogenation …

A highly efficient and metal-free [3+ 2] cyclization/rearrangement reaction toward the
synthesis of multisubstituted trifluoromethyloxazolines from α-hydroxyketones and …

An efficient direct azo-coupling reaction of trifluoromethyl N-acylhydrazones/N-aryl
hydrazones with aryldiazonium tetrafluoroborates was developed for the synthesis of …

A highly efficient, metal-free, chemical oxidation of hydrazines has been implemented using
environmentally friendly TCCA as oxidant. This benign protocol provides straightforward …

Trifluoromethylated N‐acylhydrazones are used as dipolarophiles to perform 1, 3‐dipolar
cycloadditions with azomethine ylides to afford trifluoromethylated 1, 2, 4, 5‐tetrasubstituted …

A highly efficient strategy for the construction of CF3-substituted 1, 6-dihydropyridazines has
been developed by cascade oxidation/cyclization of trifluoromethylated N-acylhydrazines …