Advances in multicellular spheroids formation
Three-dimensional multicellular spheroids (MCSs) have a complex architectural structure,
dynamic cell–cell/cell–matrix interactions and bio-mimicking in vivo microenvironment. As a …
dynamic cell–cell/cell–matrix interactions and bio-mimicking in vivo microenvironment. As a …
Spheroids-on-a-chip: Recent advances and design considerations in microfluidic platforms for spheroid formation and culture
A cell spheroid is a three-dimensional (3D) aggregation of cells. Synthetic, in-vitro spheroids
provide similar metabolism, proliferation, and species concentration gradients to those found …
provide similar metabolism, proliferation, and species concentration gradients to those found …
Cell spheroids as a versatile research platform: formation mechanisms, high throughput production, characterization and applications
MC Decarli, R Amaral, DP Dos Santos, LB Tofani… - …, 2021 - iopscience.iop.org
Abstract Three-dimensional (3D) cell culture has tremendous advantages to closely mimic
the in vivo architecture and microenvironment of healthy tissue and organs, as well as of …
the in vivo architecture and microenvironment of healthy tissue and organs, as well as of …
Heart repair using nanogel-encapsulated human cardiac stem cells in mice and pigs with myocardial infarction
J Tang, X Cui, TG Caranasos, MT Hensley… - Acs Nano, 2017 - ACS Publications
Stem cell transplantation is currently implemented clinically but is limited by low retention
and engraftment of transplanted cells and the adverse effects of inflammation and …
and engraftment of transplanted cells and the adverse effects of inflammation and …
A 3D view of colorectal cancer models in predicting therapeutic responses and resistance
Simple Summary Colorectal cancer is one of the most common solid tumors in the
developed world. Although there have being many advances in treatment options in recent …
developed world. Although there have being many advances in treatment options in recent …
Predicting and elucidating the post-printing behavior of 3D printed cancer cells in hydrogel structures by integrating in-vitro and in-silico experiments
D Mohammadrezaei, N Moghimi, S Vandvajdi… - Scientific Reports, 2023 - nature.com
A key feature distinguishing 3D bioprinting from other 3D cell culture techniques is its
precise control over created structures. This property allows for the high-resolution …
precise control over created structures. This property allows for the high-resolution …
Digital twins for tissue culture techniques—concepts, expectations, and state of the art
Techniques to provide in vitro tissue culture have undergone significant changes during the
last decades, and current applications involve interactions of cells and organoids, three …
last decades, and current applications involve interactions of cells and organoids, three …
Multifunctional alginate-based hydrogel with reversible crosslinking for controlled therapeutics delivery
Glycan-based alginate hydrogels have great potential in creating new vehicles with
responsive behavior and tunable properties for biomedicine. However, precise control and …
responsive behavior and tunable properties for biomedicine. However, precise control and …
3D printing of a thermosensitive hydrogel for skin tissue engineering: A proof of concept study
Because of important functions of skin, an effective therapy is demanded for serious full-
thickness skin injuries. In this study, a thermosensitive poly (N-isopropylacrylamide-co …
thickness skin injuries. In this study, a thermosensitive poly (N-isopropylacrylamide-co …
[HTML][HTML] 3D bioprinted GelMA platform for the production of lung tumor spheroids
The study proposes a platform for the formation and culture of non-small cell lung cancer
(NSCLC) spheroids, to obtain an in vitro model suitable for drug and therapy testing. To …
(NSCLC) spheroids, to obtain an in vitro model suitable for drug and therapy testing. To …