PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs that associate with
proteins of the PIWI clade of the Argonaute family. First identified in animal germ line cells …

Non-coding RNA has aroused great research interest recently, they play a wide range of
biological functions, such as regulating cell cycle, cell proliferation, and intracellular …

Recent studies have revealed a surprising diversity of sex chromosomes in vertebrates.
However, the detailed mechanism of their turnover is still elusive. To understand this …

PIWI proteins are known as mediators of transposon silencing in animal germlines but are
also found in adult pluripotent stem cells of highly regenerative animals, where they are …

Infantile striatonigral degeneration is caused by a homozygous variant of the nuclear‐pore
complex (NPC) gene NUP62, involved in nucleo‐cytoplasmic trafficking. By querying …

Background Female reproductive behaviors and physiology change profoundly after mating.
The control of pregnancy-associated changes in physiology and behaviors are largely hard …

The gene-regulatory mechanisms controlling the expression of the germline PIWI-interacting
RNA (piRNA) pathway components within the gonads of metazoan species remain largely …

Animal, protist and viral messenger RNAs (mRNAs) are most prominently modified at the
beginning by methylation of cap‐adjacent nucleotides at the 2′‐O‐position of the ribose …

One of the remarkable features of eukaryotes is the nucleus, delimited by the nuclear
envelope (NE), a complex structure and home to the nuclear lamina and nuclear pore …

Background The piRNA pathway in animal gonads functions as an 'RNA-based immune
system', serving to silence transposable elements and prevent inheritance of novel invaders …