Sex-based differences in human disease are caused in part by the levels of endogenous
sex steroid hormones which regulate mitochondrial metabolism. This review updates a …

Endometriosis occurs when endometrial-like tissue forms and grows outside the uterus due
to oestrogen-induced epithelial-mesenchymal transition in the female reproductive tract …

Simple Summary If improvements of diagnostic techniques and methodologies allow to
increasingly detect cancers at the premetastatic stage, metastases still account for about …

Abstract Treatment options for brain metastatic breast cancer are limited because the
molecular mechanism for how breast cancer cells infiltrate the brain is not fully understood …

Simple Summary Adoptive immunotherapy utilizing ex vivo expanded natural killer (NK)
cells is being explored in the clinical and preclinical settings to treat hematological tumors …

Purpose Nuclear respiratory factor 1 (NRF1) drives estrogen-dependent breast
tumorigenesis. Herein we examined the impact of NRF1 activity on the aggressiveness and …

Background Nuclear respiratory factor 1 (NRF1) is a transcription factor that participates in
several kinds of tumor, but its role in hepatocellular carcinoma (HCC) remains elusive. This …

Simple Summary ZNF582-AS1 expression is lower in breast cancer compared to adjacent
normal tissues, and low expression is associated with poor disease-free and overall …

Aims Lung adenocarcinoma consists of multiple therapeutic targets, however, patients will
inevitably progress to later stage diagnosis with Tyrosine Kinase Inhibitor treatment …

Metabolic plasticity is the ability of the cell to adjust its metabolism to changes in
environmental conditions. Increased metabolic plasticity is a defining characteristic of cancer …