[HTML][HTML] Estrogenic control of mitochondrial function
CM Klinge - Redox biology, 2020 - Elsevier
Sex-based differences in human disease are caused in part by the levels of endogenous
sex steroid hormones which regulate mitochondrial metabolism. This review updates a …
sex steroid hormones which regulate mitochondrial metabolism. This review updates a …
Oestrogen-induced epithelial-mesenchymal transition (EMT) in endometriosis: Aetiology of vaginal agenesis in Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome
T Lih Yuan, N Sulaiman, AG Nur Azurah… - Frontiers in …, 2022 - frontiersin.org
Endometriosis occurs when endometrial-like tissue forms and grows outside the uterus due
to oestrogen-induced epithelial-mesenchymal transition in the female reproductive tract …
to oestrogen-induced epithelial-mesenchymal transition in the female reproductive tract …
Inhibition of mitochondrial redox signaling with MitoQ prevents metastasis of human pancreatic cancer in mice
T Capeloa, JA Van de Velde, D d'Hose, SG Lipari… - Cancers, 2022 - mdpi.com
Simple Summary If improvements of diagnostic techniques and methodologies allow to
increasingly detect cancers at the premetastatic stage, metastases still account for about …
increasingly detect cancers at the premetastatic stage, metastases still account for about …
Brain infiltration of breast cancer stem cells is facilitated by paracrine signaling by inhibitor of differentiation 3 to nuclear respiratory factor 1
Abstract Treatment options for brain metastatic breast cancer are limited because the
molecular mechanism for how breast cancer cells infiltrate the brain is not fully understood …
molecular mechanism for how breast cancer cells infiltrate the brain is not fully understood …
RNA-seq analysis reveals CCR5 as a key target for CRISPR gene editing to regulate in vivo NK cell trafficking
ER Levy, JA Clara, RN Reger, DSJ Allan, RW Childs - Cancers, 2021 - mdpi.com
Simple Summary Adoptive immunotherapy utilizing ex vivo expanded natural killer (NK)
cells is being explored in the clinical and preclinical settings to treat hematological tumors …
cells is being explored in the clinical and preclinical settings to treat hematological tumors …
Sensitivity to differential NRF1 gene signatures contributes to breast cancer disparities
Purpose Nuclear respiratory factor 1 (NRF1) drives estrogen-dependent breast
tumorigenesis. Herein we examined the impact of NRF1 activity on the aggressiveness and …
tumorigenesis. Herein we examined the impact of NRF1 activity on the aggressiveness and …
Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis
R Liu, C Yin, P Zhao, B Guo, W Ke, X Zheng, D Xie… - Biology Direct, 2023 - Springer
Background Nuclear respiratory factor 1 (NRF1) is a transcription factor that participates in
several kinds of tumor, but its role in hepatocellular carcinoma (HCC) remains elusive. This …
several kinds of tumor, but its role in hepatocellular carcinoma (HCC) remains elusive. This …
LncRNA ZNF582-AS1 Expression and Methylation in Breast Cancer and Its Biological and Clinical Implications
Simple Summary ZNF582-AS1 expression is lower in breast cancer compared to adjacent
normal tissues, and low expression is associated with poor disease-free and overall …
normal tissues, and low expression is associated with poor disease-free and overall …
TUSC7 suppression of Notch activation through sponging MiR-146 recapitulated the asymmetric cell division in lung adenocarcinoma stem cells
G Huang, M Wang, X Li, J Wu, S Chen, N Du, K Li… - Life sciences, 2019 - Elsevier
Aims Lung adenocarcinoma consists of multiple therapeutic targets, however, patients will
inevitably progress to later stage diagnosis with Tyrosine Kinase Inhibitor treatment …
inevitably progress to later stage diagnosis with Tyrosine Kinase Inhibitor treatment …
Energy metabolic plasticity of colorectal cancer cells as a determinant of tumor growth and metastasis
L Reinsalu, M Puurand, V Chekulayev, S Miller… - Frontiers in …, 2021 - frontiersin.org
Metabolic plasticity is the ability of the cell to adjust its metabolism to changes in
environmental conditions. Increased metabolic plasticity is a defining characteristic of cancer …
environmental conditions. Increased metabolic plasticity is a defining characteristic of cancer …