Role of animal models in biomedical research: a review

P Mukherjee, S Roy, D Ghosh, SK Nandi - Laboratory Animal Research, 2022 - Springer
The animal model deals with the species other than the human, as it can imitate the disease
progression, its' diagnosis as well as a treatment similar to human. Discovery of a drug …

Mesenchymal stem cells: amazing remedies for bone and cartilage defects

P Kangari, T Talaei-Khozani… - Stem Cell Research & …, 2020 - Springer
Skeletal disorders are among the leading debilitating factors affecting millions of people
worldwide. The use of stem cells for tissue repair has raised many promises in various …

Large animal models in regenerative medicine and tissue engineering: to do or not to do

I Ribitsch, PM Baptista, A Lange-Consiglio… - … in Bioengineering and …, 2020 - frontiersin.org
Rapid developments in Regenerative Medicine and Tissue Engineering has witnessed an
increasing drive toward clinical translation of breakthrough technologies. However, the …

The meniscus tear: a review of stem cell therapies

G Jacob, K Shimomura, AJ Krych, N Nakamura - Cells, 2019 - mdpi.com
Meniscal injuries have posed a challenging problem for many years, especially considering
that historically the meniscus was considered to be a structure with no important role in the …

The burden of meniscus injury in young and physically active populations

SM Gee, DJ Tennent, KL Cameron… - Clinics in sports …, 2020 - sportsmed.theclinics.com
Meniscus injuries are common in pediatric and adult populations. Although tears are more
often symptomatic in young and physically active patients, they are more prevalent in older …

[HTML][HTML] Stem cell treatment for knee articular cartilage defects and osteoarthritis

A Arshi, FA Petrigliano, RJ Williams… - Current reviews in …, 2020 - Springer
Abstract Purpose of Review To review the current basic science and clinical literature on
mesenchymal stem cell (MSC) therapy for articular cartilage defects and osteoarthritis of the …

Bone marrow concentrate injections for the treatment of osteoarthritis: evidence from preclinical findings to the clinical application

C Cavallo, A Boffa, L Andriolo, S Silva, B Grigolo… - International …, 2021 - Springer
Purpose To investigate the available literature on the use of bone marrow aspirate
concentrate (BMAC) and summarize the current evidence supporting its potential for the …

Meniscus repair and regeneration: a systematic review from a basic and translational science perspective

J Twomey-Kozak, C Jayasuriya - Clinics in sports medicine, 2020 - pmc.ncbi.nlm.nih.gov
Meniscus injuries are among the most common athletic injuries and result in functional
impairment in the knee. Repair is crucial for pain relief and prevention of degenerative joint …

How do mesenchymal stem cells influence or are influenced by microenvironment through extracellular vesicles communication?

G Dostert, B Mesure, P Menu, É Velot - Frontiers in Cell and …, 2017 - frontiersin.org
Mesenchymal stem cells (MSCs) are widely used in cell therapy and tissue engineering
thanks to their self-renewal, their multipotency, and their immunomodulatory properties that …

A roadmap of in vitro models in osteoarthritis: a focus on their biological relevance in regenerative medicine

I Bartolotti, L Roseti, M Petretta, B Grigolo… - Journal of clinical …, 2021 - mdpi.com
Osteoarthritis (OA) is a multifaceted musculoskeletal disorder, with a high prevalence
worldwide. Articular cartilage and synovial membrane are among the main biological targets …