It has been known for some time that HIV‐1 virions contain cellular proteins in addition to
proteins encoded by the viral genome. Recent studies have vastly increased the number of …

Antibodies (Abs) are the major component of the humoral immune response and a key
player in vaccination. The precise Ab-mediated inhibitory mechanisms leading to in vivo …

B cells produce a plethora of anti-HIV antibodies (Abs) but only few of them exhibit
neutralizing activity. This was long considered a profound limitation for the enforcement of …

Humoral immunity is considered a key component of effective vaccines against HIV‐1.
Hence, an enormous effort has been put into investigating the neutralizing antibody …

After producing triple (Gal, HD and Sda)-KO pigs, hyperacute rejection appeared to no
longer be a problem. However, the origin of xeno-rejection continues to be a controversial …

The complement system, a key component of innate immunity, is a first-line defender against
foreign pathogens such as HIV-1. The role of the complement system in HIV-1 pathogenesis …

Novel tools are necessary to understand mechanisms of altered susceptibility to HIV-1
infection in women of the Pumwani Sex Worker cohort, Kenya. In this cohort, more than 140 …

The complement system, a key component of innate immunity, provides the first line of
defense against bacterial infection; however, the COVID-19 pandemic has revealed that it …

Over the past decade, a wealth of experimental evidence has accumulated supporting the
importance of Fc receptor (FcR) ligation in antibody‐mediated pathology and protection in …

Immature dendritic cells (iDCs) in genital and rectal mucosa may be one of the first cells to
come into contact with HIV-1 during sexual transmission of virus. HIV-1 activates the host …