Mesenchymal stromal cell secretome for the treatment of immune-mediated inflammatory diseases: latest trends in isolation, content optimization and delivery …

E Munoz-Perez, A Gonzalez-Pujana, M Igartua… - Pharmaceutics, 2021 - mdpi.com
Considering the high prevalence and the complex pharmacological management of immune-
mediated inflammatory diseases (IMIDs), the search for new therapeutic approaches for their …

[HTML][HTML] Mesenchymal stem cell treatment for COVID-19

R Xu, Z Feng, FS Wang - EBioMedicine, 2022 - thelancet.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has caused a
global pandemic since late 2019 that resulted in more than 360 million population infection …

SARS-CoV-2 infection and lung regeneration

F Zhao, Q Ma, Q Yue, H Chen - Clinical Microbiology Reviews, 2022 - Am Soc Microbiol
The lung is the primary site of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2)-induced immunopathology whereby the virus enters the host cells by binding to …

Bone marrow-derived mesenchymal stromal cell therapy in severe COVID-19: preliminary results of a phase I/II clinical trial

C Grégoire, N Layios, B Lambermont… - Frontiers in …, 2022 - frontiersin.org
Background Treatment of acute respiratory distress syndrome (ARDS) associated with
COronaVIrus Disease-2019 (COVID-19) currently relies on dexamethasone and supportive …

The safety and efficacy of mesenchymal stromal cells in ARDS: a meta-analysis of randomized controlled trials

F Wang, Y Li, B Wang, J Li, Z Peng - Critical Care, 2023 - Springer
Mesenchymal stromal cells (MSC) have shown potential efficacy in both animal and human
trials of acute respiratory distress syndrome (ARDS). Especially during the COVID-19 …

Systematic review and meta-analysis of cell therapy for COVID-19: global clinical trial landscape, published safety/efficacy outcomes, cell product manufacturing and …

PS Couto, N Al-Arawe, IS Filgueiras… - Frontiers in …, 2023 - frontiersin.org
During the pandemic of severe respiratory distress syndrome coronavirus 2 (SARS-CoV2),
many novel therapeutic modalities to treat Coronavirus 2019 induced disease (COVID-19) …

Effectiveness and safety of normoxic allogenic umbilical cord mesenchymal stem cells administered as adjunctive treatment in patients with severe COVID-19

B Soetjahjo, RG Malueka, A Nurudhin, Purwoko… - Scientific Reports, 2023 - nature.com
Inflammatory response in COVID-19 contributes greatly to disease severity. Mesenchymal
Stem Cells (MSCs) have the potential to alleviate inflammation and reduce mortality and …

Umbilical cord blood transplantation: connecting its origin to its future

G Sanchez-Petitto, K Rezvani, M Daher… - Stem cells …, 2023 - academic.oup.com
Transplantation of umbilical cord blood (UCB) is an attractive alternative source of
hematopoietic stem cells (HSCs). The unique properties of cord blood and its distinct …

Current status of cell-based therapies for COVID-19: evidence from mesenchymal stromal cells in sepsis and ARDS

Z Xu, Y Huang, J Zhou, X Deng, W He, X Liu… - Frontiers in …, 2021 - frontiersin.org
The severe respiratory consequences of the coronavirus disease 2019 (COVID-19)
pandemic have prompted the urgent need for novel therapies. Cell-based therapies …

Stem cell-based therapy for COVID-19 and ARDS: a systematic review

G Zanirati, L Provenzi, LL Libermann… - NPJ Regenerative …, 2021 - nature.com
Despite global efforts to establish effective interventions for coronavirus disease 2019
(COVID-19) and its major complications, such as acute respiratory distress syndrome …