Therapeutic vaccines for HPV-associated malignancies

C Smalley Rumfield, N Roller, ST Pellom… - ImmunoTargets and …, 2020 - Taylor & Francis
Human papillomavirus (HPV)-related malignancies are responsible for almost all cases of
cervical cancer in women, and over 50% of all cases of head and neck carcinoma …

Vaccines for HPV-associated diseases

JM Skolnik, MP Morrow - Molecular Aspects of Medicine, 2023 - Elsevier
Human papillomavirus (HPV) infection represents a significant global health concern owing
to its role in the etiology of conditions ranging from benign low-grade lesions to cancers of …

HNSCC: tumour antigens and their targeting by immunotherapy

A von Witzleben, C Wang, S Laban, N Savelyeva… - Cells, 2020 - mdpi.com
Head and neck squamous cell carcinomas (HNSCC) are a heterogeneous group of
malignant tumours typically caused by alcohol and tobacco consumption, although an …

Immunotherapy approaches in HPV-associated head and neck cancer

R Julian, M Savani, JE Bauman - Cancers, 2021 - mdpi.com
Simple Summary Human papillomavirus (HPV)-positive head and neck squamous cell
carcinoma (HNSCC) represents a distinct entity with molecular, pathological, and clinical …

Immune checkpoints pathways in head and neck squamous cell carcinoma

F Veigas, YD Mahmoud, J Merlo, A Rinflerch… - Cancers, 2021 - mdpi.com
Simple Summary During the last decades, scientific advances in immuno-oncology and a
better understanding of tumors' immune profile led to the development of novel …

Overcoming resistance to immune checkpoint inhibitors in head and neck squamous cell carcinomas

LV Dos Santos, CM Abrahão, WN William Jr - Frontiers in oncology, 2021 - frontiersin.org
Preclinical data suggest that head and neck squamous cell carcinomas (HNSCC) may
evade immune surveillance and induce immunosuppression. One mechanism of immune …

The role of different immunocompetent cell populations in the pathogenesis of head and neck cancer—regulatory mechanisms of pro-and anti-cancer activity and their …

K Starska-Kowarska - Cancers, 2023 - mdpi.com
Simple Summary According to the latest GLOBOCAN data, head and neck squamous cell
carcinoma (HNSCC) represents the sixth most prevalent human malignancy. Recent studies …

Recent developments in immunotherapy of cancers caused by human papillomaviruses

E Fakhr, Ž Modic, A Cid‐Arregui - Immunology, 2021 - Wiley Online Library
A subset of oncogenic human papillomaviruses (HPVs) is the main cause of genital cancers,
most importantly cervical cancer and an increasing number of head and neck cancers …

Monoclonal antibodies in cervical malignancy-related HPV

PS Aghbash, N Hemmat, H Fathi, HB Baghi - Frontiers in Oncology, 2022 - frontiersin.org
Despite many efforts to treat HPV infection, cervical cancer survival is still poor for several
reasons, including resistance to chemotherapy and relapse. Numerous treatments such as …

Head and neck squamous cell carcinoma vaccine: Current landscape and perspectives

PG Meliante, C Petrella, M Fiore, A Minni… - Current Issues in …, 2023 - mdpi.com
The treatment of unresectable or metastatic Head and Neck Squamous Cell Carcinoma
(HNSCC) has traditionally relied on chemotherapy or radiotherapy, yielding suboptimal …