Background: To recognize the action of pharmacologically approved anticancer drugs in
biological systems, information regarding its pharmacokinetics, such as its transport within …

Lenvatinib was a multi-tyrosine kinase inhibitor (TKI) used for treating advanced renal cell
carcinoma and differentiated thyroid cancer. Multiple fluorescence spectroscopy including …

Simple Summary Cancer is one of the biggest causes of death world-wide. The
development of anti-cancer drugs is important in combatting this disease. As good as these …

A protein-polysaccharide-based potential nanocarrier system have been developed via a
simple, one-step preparation protocol without the use of long-term heating and the utilization …

Although tyrosine kinase inhibitors (TKIs) have revolutionized cancer therapy in the past two
decades, severe drawbacks such as strong adverse effects and drug resistance limit their …

Pancreatic cancer is one of the most lethal cancers, with an extremely poor prognosis. The
development of more effective therapies is thus imperative. Natural origin compounds …

Fibroblast growth factor receptors (FGFRs) have emerged as promising targets for
anticancer therapy. In this study, we synthesized and evaluated the biological activity of 66 …

It is important for elucidating the regulation mechanism of life activities, as well as for the
prevention, diagnosis, and drug design of diseases, to study protein–protein interactions …

Unlike many other plasma proteins, albumin is barely glycosylated and plays an important
role in maintaining the colloidal osmotic blood pressure; it can bind and transport various …

We report on the unique self-assembling properties of one molybdacarborane (1) and two
ruthenacarborane complexes (2 and 3) to spontaneously form nanoparticles alone or in …