Context.—Numerous immunohistochemical stains have been shown to exhibit exclusive or
preferential positivity in breast myoepithelial cells relative to their luminal/epithelial …

Hydrogen sulfide (H 2 S) is considered as a novel second-messenger molecule associated
with the modulation of various physiological and pathological processes. In the field of …

MicroRNAs play important roles in regulating the gene expression and life cycle of cancer
cells. In particular, miR-21, an oncogenic miRNA is a major player involved in tumor …

Although Wnt/β-catenin pathway activation has been implicated in mouse models of breast
cancer, there is contradictory evidence regarding its importance in human breast cancer. In …

Triple-negative breast cancer (TNBC) is an aggressive disease with a short median time
from relapse to death. The increased aggressiveness, drug resistance, disease relapse, and …

Purpose: Although the murine orthologue of glycoprotein nonmetastatic B (GPNMB),
Osteoactivin, promotes breast cancer metastasis in an in vivo mouse model, its importance …

Abstract Introduction Basal-like carcinomas (BLCs) and human epidermal growth factor
receptor 2 overexpressing (HER2+) carcinomas are the subgroups of breast cancers that …

Background Basal-like constitutes an important molecular subtype of breast cancer
characterised by an aggressive behaviour and a limited therapy response. The outcome of …

Triple-negative breast cancer (TNBC) represents a subgroup of breast cancers (BC)
associated with the most aggressive clinical behavior. No targeted therapy is currently …

Advances in basic science, technology and translational research have created a revolution
in breast cancer diagnosis and therapy. Researchers' discoveries of genes defining …