Anaplasma marginale and Anaplasma phagocytophilum: Rickettsiales pathogens of veterinary and public health significance

FA Atif - Parasitology research, 2015 - Springer
Anaplasma marginale and Anaplasma phagocytophilum are the most important tick-borne
bacteria of veterinary and public health significance in the family Anaplasmataceae. The …

Longitudinal TprK profiling of in vivo and in vitro-propagated Treponema pallidum subsp. pallidum reveals accumulation of antigenic variants in absence of immune …

MJ Lin, AM Haynes, A Addetia… - PLoS Neglected …, 2021 - journals.plos.org
Immune evasion by Treponema pallidum subspecies pallidum (T. pallidum) has been
attributed to antigenic variation of its putative outer-membrane protein TprK. In TprK, amino …

Functional and Immunological Relevance of Anaplasma marginale Major Surface Protein 1a Sequence and Structural Analysis

A Cabezas-Cruz, LMF Passos, K Lis, R Kenneil… - PLoS …, 2013 - journals.plos.org
Bovine anaplasmosis is caused by cattle infection with the tick-borne bacterium, Anaplasma
marginale. The major surface protein 1a (MSP1a) has been used as a genetic marker for …

An Ixodes scapularis cell line with a predominantly neuron-like phenotype

JD Oliver, ASO Chávez, RF Felsheim, TJ Kurtti… - … and Applied Acarology, 2015 - Springer
The Ixodes scapularis embryo-derived cell line ISE6 is the most widely utilized tick-derived
cell line due to its susceptibility to a wide variety of tick-and non-tick-vectored pathogens …

Genetic diversity and molecular phylogeny of Anaplasma marginale studied longitudinally under natural transmission conditions in Rio de Janeiro, Brazil

JB Silva, LR Goncalves, A de Mello Varani… - Ticks and Tick-Borne …, 2015 - Elsevier
Anaplasma marginale is the most prevalent tick-borne pathogen in cattle in tropical and
subtropical regions of the world. Major Surface Protein 1a (MSP1a) has been found to be a …

Global Transcription Profiles of Anaplasma phagocytophilum at Key Stages of Infection in Tick and Human Cell Lines and Granulocytes

CM Nelson, MJ Herron, XR Wang… - Frontiers in Veterinary …, 2020 - frontiersin.org
The incidence of human diseases caused by tick-borne pathogens is increasing but little is
known about the molecular interactions between the agents and their vectors and hosts …

Molecular characterization of Anaplasma marginale based on the msp1a and msp1b genes

W Junsiri, A Watthanadirek, N Poolsawat… - Veterinary …, 2021 - Elsevier
Anaplasma marginale is an intracellular rickettsial bacterium causing anaplasmosis in
ruminants. A. marginale is transmitted biologically by ticks and mechanically by blood …

Mutational analysis of gene function in the Anaplasmataceae: Challenges and perspectives

ASO Chávez, MJ Herron, CM Nelson… - Ticks and tick-borne …, 2019 - Elsevier
Mutational analysis is an efficient approach to identifying microbial gene function. Until
recently, lack of an effective tool for Anaplasmataceae yielding reproducible results has …

Tissue Distribution of the Ehrlichia muris-Like Agent in a Tick Vector

GE Lynn, JD Oliver, CM Nelson, RF Felsheim… - PLoS …, 2015 - journals.plos.org
Human pathogens transmitted by ticks undergo complex life cycles alternating between the
arthropod vector and a mammalian host. While the latter has been investigated to a greater …

Biostatistical prediction of genes essential for growth of Anaplasma phagocytophilum in a human promyelocytic cell line using a random transposon mutant library

MC O'Conor, MJ Herron, CM Nelson… - Pathogens and …, 2021 - academic.oup.com
Anaplasma phagocytophilum (Ap), agent of human anaplasmosis, is an intracellular
bacterium that causes the second most common tick-borne illness in North America. To …