Natural products (NPs) are a major source of compounds for medical, agricultural, and
biotechnological industries. Many of these compounds are of microbial origin, and, in …

The two‐component regulatory system CiaRH of Streptococcus pneumoniae has been
implicated in β‐lactam resistance, maintenance of cell integrity, competence and virulence …

In the post-genomic area, the prediction of transcription factor regulons by position weight
matrix-based programmes is a powerful approach to decipher biological pathways and to …

Neisseria meningitidis (Nm) and N. gonorrhoeae (Ng) are adapted to different environments
within their human host. If the basis of this difference has not yet been fully understood …

Metal ion availability in the human oral cavity plays a putative role in Streptococcus mutans
virulence gene expression and in appropriate formation of the plaque biofilm. In this report …

RegTransBase is a manually curated database of regulatory interactions in prokaryotes that
captures the knowledge in public scientific literature using a controlled vocabulary. Although …

The published genome sequences of Corynebacterium diphtheriae, Corynebacterium
efficiens, Corynebacterium glutamicum and Corynebacterium jeikeium were screened for …

We have characterized group A Streptococcus (GAS) genome-wide responses to hydrogen
peroxide and assessed the role of the peroxide response regulator (PerR) in GAS under …

The peroxide response transcriptional regulator, PerR, is thought to contribute to virulence of
group A Streptococcus (GAS); however, the specific mechanism through which it enhances …

IdeR (iron-dependent regulator) is a key regulator of virulence factors and iron acquisition
systems in Mycobacterium tuberculosis. Despite the wealth of information available on IdeR …