Advances in the physiology of gastric emptying

RK Goyal, Y Guo, H Mashimo - Neurogastroenterology & …, 2019 - Wiley Online Library
There have been many recent advances in the understanding of various aspects of the
physiology of gastric motility and gastric emptying. Earlier studies had discovered the …

Effects of GLP-1 and its analogs on gastric physiology in diabetes mellitus and obesity

DB Maselli, M Camilleri - Diabetes: from Research to Clinical Practice …, 2021 - Springer
The processing of proglucagon in intestinal L cells results in the formation of glucagon, GLP-
1, and GLP-2. The GLP-1 molecule becomes active through the effect of proconvertase 1 …

Emerging role of PLAG1 as a regulator of growth and reproduction

AR Juma, PE Damdimopoulou… - Journal of …, 2016 - joe.bioscientifica.com
Anti-Müllerian hormone (AMH) is a multi-faceted gonadal cytokine. It is present in all
vertebrates with its original function in phylogeny being as a regulator of germ cells in both …

Ligilactobacillus Salivarius LCK11 Prevents Obesity by Promoting PYY Secretion to Inhibit Appetite and Regulating Gut Microbiota in C57BL/6J Mice

C Liang, XH Zhou, YH Jiao, MJ Guo… - Molecular nutrition & …, 2021 - Wiley Online Library
Scope Obesity is a common disease worldwide and there is an urgent need for strategies to
preventing obesity. Methods and Results The anti‐obesity effect and mechanism of …

NUCB2/nesfatin-1–Inhibitory effects on food intake, body weight and metabolism

MA Schalla, S Unniappan, NWG Lambrecht, M Mori… - Peptides, 2020 - Elsevier
Since its discovery in 2006 by Oh-I and colleagues, NUCB2/nesfatin-1 encoded by
nucleobindin-2 (NUCB2) has drawn sustained attention as reflected in over 500 …

Intestinal NUCB2/nesfatin-1 regulates hepatic glucose production via the MC4R-cAMP-GLP-1 pathway

S Geng, S Yang, X Tang, S Xue, K Li, D Liu… - The EMBO …, 2024 - embopress.org
Communication of gut hormones with the central nervous system is important to regulate
systemic glucose homeostasis, but the precise underlying mechanism involved remain little …

Ghrelin Facilitates GLUT2-, SGLT1- and SGLT2-mediated Intestinal Glucose Transport in Goldfish (Carassius auratus)

AM Blanco, JI Bertucci, N Ramesh, MJ Delgado… - Scientific Reports, 2017 - nature.com
Glucose homeostasis is an important biological process that involves a variety of regulatory
mechanisms. This study aimed to determine whether ghrelin, a multifunctional gut-brain …

FGF21 mimics a fasting-induced metabolic state and increases appetite in zebrafish

AM Blanco, JI Bertucci, S Unniappan - Scientific Reports, 2020 - nature.com
Abstract Fibroblast growth factor 21 (FGF21) is a member of the FGF superfamily that acts in
an endocrine manner. FGF21 is a key regulator of energy balance and metabolism in …

Ghrelin suppresses cholecystokinin (CCK), peptide YY (PYY) and glucagon-like peptide-1 (GLP-1) in the intestine, and attenuates the anorectic effects of CCK, PYY …

AM Blanco, JI Bertucci, AI Valenciano, MJ Delgado… - Hormones and …, 2017 - Elsevier
Ghrelin is an important gut-derived hormone with an appetite stimulatory role, while most of
the intestinal hormones, including cholecystokinin (CCK), peptide YY (PYY) and glucagon …

Alterations in small intestine and liver morphology, immunolocalization of leptin, ghrelin and nesfatin-1 as well as immunoexpression of tight junction proteins in …

I Puzio, S Muszyński, P Dobrowolski, M Kapica… - Journal of Clinical …, 2021 - mdpi.com
The stomach is responsible for the processing of nutrients as well as for the secretion of
various hormones which are involved in many activities throughout the gastrointestinal tract …