Microsatellites form a significant proportion of the growing family of repetitive DNA
sequences, widely dispersed in the human genome. Due to their ubiquity, PCR (polymerase …

Trinucleotide microsatellites have proven to be the markers of choice in human genetic
analysis because they are easier to genotype than dinucleotides. Their development can be …

Ependymomas arise from the ependymal cells at different locations throughout the brain and
spinal cord. These tumors have a broad age distribution with a range from less than 1 year …

Autosomal, dominantly inherited, non-chromaffin paragangliomas are tumors of the head
and neck region occurring with a frequency of 1∶ 30 000. Genomic imprinting probably …

Familial hyperinsulinism (HI) is the most common cause of persistent neonatal
hyperinsulinaemic hypoglycemia. Linkage analysis in 15 families (12 Ashkenazi Jewish, 2 …

Infection of cervical epithelial cells with so-called" aggressive" subtypes of human papilloma
virus (HPV) appears to be an important factor in the etiology of cervical carcinoma. However …

We present a high resolution radiation hybrid map of human chromosome 11 using 506
sequence tagged sites (STSs) scored on a panel of 86 radiation hybrids. The 506 STSs fall …

Background: Meiotic recombination events do not occur randomly along a chromosome, but
appear to be restricted to specific regions. In addition, some regions in the genome undergo …

We describe a 20-point linkage analysis map of chromosome 11q22-23 that is based on
genotyping 249 families (59 CEPH and 190 AT). Monte Carlo linkage analyses of 176 ataxia …

Familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI) is a rare, autosomal
recessive disease of unregulated insulin secretion, defined by elevations in serum insulin …