Potential toxic effects of glyphosate and its commercial formulations below regulatory limits

R Mesnage, N Defarge, JS De Vendômois… - Food and Chemical …, 2015 - Elsevier
Abstract Glyphosate-based herbicides (GlyBH), including Roundup, are the most widely
used pesticides worldwide. Their uses have increased exponentially since their introduction …

Glyphosate uptake, translocation, resistance emergence in crops, analytical monitoring, toxicity and degradation: a review

S Singh, V Kumar, S Datta, AB Wani… - Environmental chemistry …, 2020 - Springer
The herbicide glyphosate is widely used to control weeds in grain crops. The overuse of
glyphosate has induced issues such as contamination of surface water, decreased soils …

Glyphosate toxicity: in vivo, in vitro, and epidemiological evidence

R Lacroix, DM Kurrasch - Toxicological Sciences, 2023 - academic.oup.com
Glyphosate is the most applied agricultural chemical worldwide and has become nearly
ubiquitous throughout the environment. Glyphosate is an effective herbicide because it …

Oxidative stress and metabolism: a mechanistic insight for glyphosate toxicology

X Wang, Q Lu, J Guo, I Ares, M Martínez… - Annual review of …, 2022 - annualreviews.org
Glyphosate (GLYP) is a widely used pesticide; it is considered to be a safe herbicide for
animals and humans because it targets 5-enolpyruvylshikimate-3-phosphate synthase …

[HTML][HTML] Glyphosate's suppression of cytochrome P450 enzymes and amino acid biosynthesis by the gut microbiome: pathways to modern diseases

A Samsel, S Seneff - Entropy, 2013 - mdpi.com
Note added by the Publisher: The editors of the journal have been alerted to concerns over
potential bias in opinions and bias in the choice of citation sources used in this article. We …

Multiomics reveal non-alcoholic fatty liver disease in rats following chronic exposure to an ultra-low dose of Roundup herbicide

R Mesnage, G Renney, GE Séralini, M Ward… - Scientific reports, 2017 - nature.com
The impairment of liver function by low environmentally relevant doses of glyphosate-based
herbicides (GBH) is still a debatable and unresolved matter. Previously we have shown that …

Drinking well water and occupational exposure to Herbicides is associated with chronic kidney disease, in Padavi-Sripura, Sri Lanka

C Jayasumana, P Paranagama, S Agampodi… - Environmental …, 2015 - Springer
Background The chronic kidney disease of unknown etiology (CKDu) among paddy farmers
in was first reported in 1994 and has now become most important public health issue in dry …

CKD of uncertain etiology: a systematic review

J Lunyera, D Mohottige, M Von Isenburg… - Clinical journal of the …, 2016 - journals.lww.com
Results We identified 1607 articles, of which 26 met inclusion criteria. Eighteen (69%) were
conducted in known CKDu–endemic countries: Sri Lanka (38%), Nicaragua (19%), and El …

Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in Sri Lanka?

C Jayasumana, S Gunatilake… - International journal of …, 2014 - mdpi.com
The current chronic kidney disease epidemic, the major health issue in the rice paddy
farming areas in Sri Lanka has been the subject of many scientific and political debates over …

[HTML][HTML] Developmental exposure to glyphosate-based herbicide and depressive-like behavior in adult offspring: Implication of glutamate excitotoxicity and oxidative …

D Cattani, PA Cesconetto, MK Tavares, EB Parisotto… - Toxicology, 2017 - Elsevier
We have previously demonstrated that maternal exposure to glyphosate-based herbicide
(GBH) leads to glutamate excitotoxicity in 15-day-old rat hippocampus. The present study …