Mesenchymal stromal cells are multipotent cells that are being used to treat a variety of
medical conditions. Over the past decade, there has been considerable excitement about …

Recent studies suggest that the main driving force behind the therapeutic activity observed
in mesenchymal stem cells (MSCs) are the paracrine factors secreted by these cells. These …

Brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-related kinase
receptor type B (TrkB) are widely distributed in multiple regions of the human brain …

Neurodegenerative disorders are a variety of diseases including Alzheimer's (AD),
Parkinson's (PD), and Huntington's diseases (HD), multiple sclerosis (MS) and amyotrophic …

Mesenchymal stem cells have shown regenerative properties in many tissues. This feature
had originally been ascribed to their multipotency and thus their ability to differentiate into …

Stem cells have currently gained attention in the field of medicine not only due to their ability
to repair dysfunctional or damaged cells, but also they could be used as drug delivery …

Parkinson's disease (PD) is characterized by tremor, rigidity, and bradykinesia. PD is caused
mainly by depletion of the nigrostriatal pathway. Conventional medications such as …

Stem cell transplantation is a promising tool for the treatment of neurodegenerative
disorders, including Parkinson's disease (PD); however, the therapeutic routes and …

Parkinson's disease (PD) is the second most prevalent neurodegenerative disease
characterized by severe dyskinesia due to a progressive loss of dopaminergic neurons …

At present there is no effective treatment of pathologies associated with the death of neurons
and glial cells which take place as a result of physical trauma or ischemic lesions of the …