Posttraumatic stress disorder (PTSD) is associated with high morbidity and functional
impairment in the absence of effective treatment. Exposure therapy for PTSD is a trauma …

Clinical trials are time consuming, expensive, and often burdensome on patients. Clinical
trials can fail for many reasons. This survey reviews many of these reasons and offers …

Clinicians, institutions, and policy makers use results from randomized controlled trials to
make decisions regarding therapeutic interventions for their patients and populations …

Objective To provide an overview of non-pharmacological interventions for behavioural and
psychological symptoms in dementia (BPSD). Design Systematic overview of reviews. Data …

We report a meta-analysis of virtual reality (VR) interventions for anxiety and depression
outcomes, as well as treatment attrition. We included randomized controlled trials comparing …

Clinical research should ultimately improve patient care. For this to be possible, trials must
evaluate outcomes that genuinely reflect real-world settings and concerns. However, many …

Background Cerebral palsy (CP) is a neurodevelopmental disorder resulting from an injury
to the developing brain. It is the most common form of childhood disability with prevalence …

Although psychotherapy is a well-established treatment for depression and anxiety, chatbot-
delivered psychotherapy is an emerging field that has yet to be explored in depth. This …

Importance Intensive follow-up of patients after curative surgery for colorectal cancer is
common in clinical practice, but evidence of a survival benefit is limited. Objective To …

Objective To synthesise evidence on the average bias and heterogeneity associated with
reported methodological features of randomized trials. Design Systematic review of meta …