Blocking HTLV-1/2 silent transmission in Brazil: current public health policies and proposal for additional strategies

C Rosadas, MLB Menezes… - PLoS Neglected …, 2021 - journals.plos.org
Human T-cell lymphotropic viruses 1 and 2 (HTLV-1/2) are relatively common in Brazil but
remain silent and neglected infections. HTLV-1 is associated with a range of diseases with …

Advances in preventive vaccine development against HTLV-1 infection: A systematic review of the last 35 years

CS Santana, FO Andrade, GCS da Silva… - Frontiers in …, 2023 - frontiersin.org
Introduction The Human T-lymphotropic virus type 1 (HTLV-1) was the first described human
retrovirus. It is currently estimated that around 5 to 10 million people worldwide are infected …

Efficacy of corticosteroid therapy for HTLV-1-associated myelopathy: a randomized controlled trial (HAMLET-P)

J Yamauchi, K Tanabe, T Sato, M Nakagawa… - Viruses, 2022 - mdpi.com
Corticosteroids are most commonly used to treat HTLV-1-associated myelopathy (HAM);
however, their clinical efficacy has not been tested in randomized clinical trials. This …

Current perspectives in human T-cell leukemia virus type 1 infection and its associated diseases

M Miura, T Naito, M Saito - Frontiers in Medicine, 2022 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) is a replication-competent human retrovirus
associated with two distinct types of diseases: a malignancy of mature CD4+ T cells called …

Health state utility values in people living with HTLV-1 and in patients with HAM/TSP: the impact of a neglected disease on the quality of life

C Rosadas, T Assone, M Yamashita… - PLoS neglected …, 2020 - journals.plos.org
Background: HTLV-1 is a neglected sexually transmitted infection despite being the cause of
disabling neurological disease HTLV-1-associated myelopathy/tropical spastic paraparesis …

[HTML][HTML] Late presentation of human T-lymphotropic virus type 1 infection in Spain reflects suboptimal testing strategies

C De Mendoza, L Pérez, M Fernández-Ruiz… - International Journal of …, 2022 - Elsevier
Objectives Although only 10% of persons infected with human T-lymphotropic virus type 1
(HTLV-1) may develop virus-associated illnesses over their lifetime, missing the earlier …

Antiretroviral therapy in HTLV-1 infection: an updated overview

F Marino-Merlo, E Balestrieri, C Matteucci, A Mastino… - Pathogens, 2020 - mdpi.com
The human T cell leukemic/lymphotropic virus type 1 (HTLV-1), discovered several years
ago, is the causative agent for a rapid progressive haematological malignancy, adult T cell …

Retroviral b‐Zip protein (HBZ) contributes to the release of soluble and exosomal immune checkpoint molecules in the context of neuroinflammation

J Joseph, TA Premeaux, DO Pinto… - Journal of …, 2023 - Wiley Online Library
HTLV‐I‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic,
progressive, neuroinflammatory demyelinating condition of the spinal cord. We have …

Infectious myelopathies

AM Fletcher, S Bhattacharyya - CONTINUUM: Lifelong Learning in …, 2024 - journals.lww.com
Objective Infectious myelopathy of any stage and etiology carries the potential for significant
morbidity and mortality. This article details the clinical presentation, risk factors, and key …

Viral co‐infections in leprosy: a scoping review

LAR Fróes Jr, TS Toma, RE Poderoso… - International Journal …, 2023 - Wiley Online Library
Context The most reported viral co‐infections in leprosy are human immunodeficiency virus
(HIV), human T‐cell lymphotropic virus (HTLV), hepatitis B virus (HBV), hepatitis C virus …