A lack of accepted standards and standardized phantoms suitable for the technical
validation of biophotonic instrumentation hinders the reliability and reproducibility of its …

Valvular heart disease is an increasing population health problem and, especially in the
elderly, a significant cause of morbidity and mortality. The current treatment options, such as …

Quantification of cardiac deformation and strain with 3D ultrasound takes considerable
research efforts. Nevertheless, a widespread use of these techniques in clinical practice is …

Background: Although associated with left heart pathologies, functional tricuspid
regurgitation (FTR) is often left untreated during left heart surgery. Hence, owing to its …

Soft robotic devices containing multiple actuating elements have successfully recapitulated
complex biological motion, leading to their utility in biomedical applications. However, there …

The increasing recognition of the right ventricle (RV) necessitates the development of RV-
focused interventions, devices and testbeds. In this study, we developed a soft robotic model …

The complex motion of the beating heart is accomplished by the spatial arrangement of
contracting cardiomyocytes with varying orientation across the transmural layers, which is …

In this work, a novel mock circulatory loop (MCL) is presented that is capable of simulating
both healthy cardiac function and Heart Failure with preserved Ejection Fraction (HFpEF) …

Quantifying mechanically-induced changes in the tricuspid valve extracellular matrix (ECM)
structural components, eg collagen fiber spread and distribution, is important as it …

Background Although CT-studies as well as intraoperative analyses have described broad
anatomic variations of the aortic annulus, which is predominantly found non-circular …