Histone modifications and the maintenance of telomere integrity

M Jezek, EM Green - Cells, 2019 - mdpi.com
Telomeres, the nucleoprotein structures at the ends of eukaryotic chromosomes, play an
integral role in protecting linear DNA from degradation. Dysregulation of telomeres can …

Ready, SET, Go: Post-translational regulation of the histone lysine methylation network in budding yeast

RJ Separovich, MR Wilkins - Journal of Biological Chemistry, 2021 - ASBMB
Histone lysine methylation is a key epigenetic modification that regulates eukaryotic
transcription. Here, we comprehensively review the function and regulation of the histone …

Uncoupling the distinct functions of HP1 proteins during heterochromatin establishment and maintenance

M Seman, A Levashkevich, A Larkin, F Huang… - Cell reports, 2023 - cell.com
Summary H3K9 methylation (H3K9me) marks transcriptionally silent genomic regions called
heterochromatin. HP1 proteins are required to establish and maintain heterochromatin. HP1 …

Lack of the COMPASS component Ccl1 reduces H3K4 trimethylation levels and affects transcription of secondary metabolite genes in two plant–pathogenic Fusarium …

L Studt, S Janevska, B Arndt, S Boedi… - Frontiers in …, 2017 - frontiersin.org
In the two fungal pathogens Fusarium fujikuroi and Fusarium graminearum, secondary
metabolites (SMs) are fitness and virulence factors and there is compelling evidence that the …

[HTML][HTML] Chromosome domain architecture and dynamic organization of the fission yeast genome

T Mizuguchi, J Barrowman, SIS Grewal - FEBS letters, 2015 - Elsevier
Advanced techniques including the chromosome conformation capture (3C) methodology
and its derivatives are complementing microscopy approaches to study genome …

[PDF][PDF] RETRACTED: SET1A Cooperates With CUDR to Promote Liver Cancer Growth and Hepatocyte-like Stem Cell Malignant Transformation Epigenetically

T Li, Q Zheng, J An, M Wu, H Li, X Gui, H Pu, D Lu - Molecular Therapy, 2016 - cell.com
Long noncoding RNA CUDR plays an important role during tumorigenesis. Herein, we
demonstrate that SET1A cooperates with CUDR to accelerate hepatocarcinogenesis and …

Cigarette smoke-induced inflammation: NLRP10-mediated mechanisms

G Kaur, P Bagam, R Pinkston, DP Singh, S Batra - Toxicology, 2018 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a progressive, life-threatening disease
that causes irreversible lung damage. Cigarette smoking is the chief etiologic factor for the …

H3K4 trimethylation by CclA regulates pathogenicity and the production of three families of terpenoid secondary metabolites in Colletotrichum higginsianum

JF Dallery, É Adelin, G Le Goff, S Pigné… - Molecular Plant …, 2019 - Wiley Online Library
The role of histone 3 lysine 4 (H3K4) methylation is poorly understood in plant pathogenic
fungi. Here, we analysed the function of CclA, a subunit of the COMPASS complex …

Mating-type switching by homology-directed recombinational repair: a matter of choice

G Thon, T Maki, JE Haber, H Iwasaki - Current genetics, 2019 - Springer
In eukaryotes, all DNA transactions happen in the context of chromatin that often takes part
in regulatory mechanisms. In particular, chromatin structure can regulate exchanges of DNA …

RNA binding by histone methyltransferases Set1 and Set2

C Sayou, G Millán-Zambrano… - … and cellular biology, 2017 - Am Soc Microbiol
Histone methylation at H3K4 and H3K36 is commonly associated with genes actively
transcribed by RNA polymerase II (RNAPII) and is catalyzed by Saccharomyces cerevisiae …