Ocular drug delivery: a comprehensive review
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …
Recent advances in ophthalmic preparations: Ocular barriers, dosage forms and routes of administration
The human eye is a complex organ with unique anatomy and physiology that restricts the
delivery of drugs to target ocular tissues/sites. Recent advances in the field of pharmacy …
delivery of drugs to target ocular tissues/sites. Recent advances in the field of pharmacy …
Advancements in rectal drug delivery systems: clinical trials, and patents perspective
The rectal route is an effective route for the local and systemic delivery of active
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …
pharmaceutical ingredients. The environment of the rectum is relatively constant with low …
Development of thermosensitive and mucoadhesive gels of cabotegravir for enhanced permeation and retention profiles in vaginal tissue: A proof of concept study
CK Enggi, HT Isa, S Sulistiawati, KAR Ardika… - International Journal of …, 2021 - Elsevier
As an effective anti-HIV drug, cabotegravir (CAB) is currently administered via oral and
injection routes, leading to several drawbacks, such as poor oral bioavailability and …
injection routes, leading to several drawbacks, such as poor oral bioavailability and …
Lamotrigine-loaded poloxamer-based thermo-responsive sol–gel: formulation, in vitro assessment, ex vivo permeation, and toxicology study
The present study aimed to prepare, characterize, and evaluate a thermo-responsive sol–
gel for intranasal delivery of lamotrigine (LTG), which was designed for sustained drug …
gel for intranasal delivery of lamotrigine (LTG), which was designed for sustained drug …
Tailored Doxycycline Hyclate Loaded In Situ Gel for the Treatment of Periodontitis: Optimization, In Vitro Characterization, and Antimicrobial Studies
Currently, periodontitis is treated by oral dosage forms (antibiotics) which shows systemic
side effects and failed to reach the therapeutic concentration (above minimum inhibitory …
side effects and failed to reach the therapeutic concentration (above minimum inhibitory …
[HTML][HTML] Recent advances in alginate based gastroretentive technologies for drug delivery applications
The efficacy of orally delivered medicines can be maximized through enhancing the gastric
residence period and modifying the drug release pattern according to therapeutic need …
residence period and modifying the drug release pattern according to therapeutic need …
[HTML][HTML] Gellan gum and sodium alginate in-situ gel of monocaprin for effective corneal permeation
Babies born to mothers suffering from gonorrhea may experience severe eye infections that
might culminate in loss of vision. The eyes of the neonate can are infected with Neisseria …
might culminate in loss of vision. The eyes of the neonate can are infected with Neisseria …
Concentration of a microemulsion influences the mechanical properties of ibuprofen in situ microgels
R Hamed, Y Al-Adhami, R Abu-Huwaij - International Journal of …, 2019 - Elsevier
The aim of this study was to develop an ibuprofen microemulsion (IBU–ME) incorporated
into in situ gels (microgels) for local delivery into periodontal pockets. The IBU–ME was …
into in situ gels (microgels) for local delivery into periodontal pockets. The IBU–ME was …
Evaluation of lectin nanoscaffold based in-situ gel against vulvovaginal candidiasis causing Candida biofilms using a novel ex-vivo model
J Senthilganesh, L Deepak, R Durai… - Journal of Drug Delivery …, 2022 - Elsevier
Vulvovaginal Candidiasis (VVC) remains a global issue for women of the reproductive age
group. It is mainly caused by Candida albicans and in some cases includes a co-infection …
group. It is mainly caused by Candida albicans and in some cases includes a co-infection …