Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

MA La Merrill, LN Vandenberg, MT Smith… - Nature Reviews …, 2020 - nature.com
Endocrine-disrupting chemicals (EDCs) are exogenous chemicals that interfere with
hormone action, thereby increasing the risk of adverse health outcomes, including cancer …

Long non-coding RNA in the pathogenesis of cancers

Y Chi, D Wang, J Wang, W Yu, J Yang - Cells, 2019 - mdpi.com
The incidence and mortality rate of cancer has been quickly increasing in the past decades.
At present, cancer has become the leading cause of death worldwide. Most of the cancers …

Re‐evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs

EFSA Panel on Food Contact Materials … - EFSA …, 2023 - Wiley Online Library
In 2015, EFSA established a temporary tolerable daily intake (t‐TDI) for BPA of 4 μg/kg body
weight (bw) per day. In 2016, the European Commission mandated EFSA to re‐evaluate the …

Glyphosate and the key characteristics of an endocrine disruptor: A review

JP Muñoz, TC Bleak, GM Calaf - Chemosphere, 2021 - Elsevier
Glyphosate is a large-spectrum herbicide that was introduced on the market in 1974. Due to
its important impact on the crop industry, it has been significantly diversified and expanded …

HOTAIR: a potential metastatic, drug-resistant and prognostic regulator of breast cancer

GSR Raju, E Pavitra, SS Bandaru, GL Varaprasad… - Molecular cancer, 2023 - Springer
HOX transcript antisense intergenic RNA (HOTAIR) is an oncogenic non-coding RNA whose
expression is strongly correlated with the tumor grade and prognosis of a variety of …

LncRNA HOTAIR: A master regulator of chromatin dynamics and cancer

A Bhan, SS Mandal - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2015 - Elsevier
Non-coding RNAs (ncRNAs) are emerging classes of regulatory RNA that play key roles in
various cellular and physiological processes such as in gene regulation, chromatin …

State of the evidence 2017: an update on the connection between breast cancer and the environment

JM Gray, S Rasanayagam, C Engel, J Rizzo - Environmental Health, 2017 - Springer
Background In this review, we examine the continually expanding and increasingly
compelling data linking radiation and various chemicals in our environment to the current …

Endocrine disruptors acting on estrogen and androgen pathways cause reproductive disorders through multiple mechanisms: a review

S Amir, STA Shah, C Mamoulakis, AO Docea… - International Journal of …, 2021 - mdpi.com
Increasing contamination of the environment by toxic compounds such as endocrine
disrupting chemicals (EDCs) is one of the major causes of reproductive defects in both …

Long noncoding RNA and cancer: a new paradigm

A Bhan, M Soleimani, SS Mandal - Cancer research, 2017 - AACR
In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …

Modulating epigenetic modifications for cancer therapy

LJ Castro-Muñoz, E Vázquez Ulloa… - Oncology …, 2023 - spandidos-publications.com
Cancer is a global public health concern. Alterations in epigenetic processes are among the
earliest genomic aberrations occurring during cancer development and are closely related …