IL-17 and IL-17-producing cells in protection versus pathology
KHG Mills - Nature Reviews Immunology, 2023 - nature.com
IL-17 cytokine family members have diverse biological functions, promoting protective
immunity against many pathogens but also driving inflammatory pathology during infection …
immunity against many pathogens but also driving inflammatory pathology during infection …
The IL-17 family in diseases: from bench to bedside
L Huangfu, R Li, Y Huang, S Wang - Signal Transduction and Targeted …, 2023 - nature.com
Abstract The interleukin-17 (IL-17) family comprises six members (IL-17A–17F), and
recently, all of its related receptors have been discovered. IL-17 was first discovered …
recently, all of its related receptors have been discovered. IL-17 was first discovered …
Genetic variants associated with hidradenitis suppurativa
Q Sun, KA Broadaway, SN Edmiston… - JAMA …, 2023 - jamanetwork.com
Importance Hidradenitis suppurativa (HS) is a common and severely morbid chronic
inflammatory skin disease that is reported to be highly heritable. However, the genetic …
inflammatory skin disease that is reported to be highly heritable. However, the genetic …
Biologics for hidradenitis suppurativa: evolution of the treatment paradigm
CA Maronese, C Moltrasio, G Genovese… - Expert Review of …, 2024 - Taylor & Francis
Introduction Hidradenitis suppurativa (HS) is an autoinflammatory skin disease with a high
unmet need for effective medical management. Clinically, it is characterized by inflammatory …
unmet need for effective medical management. Clinically, it is characterized by inflammatory …
Risk of psoriasis in people with hidradenitis suppurativa: A systematic review and meta-analysis
Background Hidradenitis suppurativa were associated with comorbidities in various organ
systems. Inflammatory dermatological diseases such as pyoderma gangrenosum were …
systems. Inflammatory dermatological diseases such as pyoderma gangrenosum were …
Short-term effectiveness, safety, and potential predictors of response of secukinumab in patients with severe hidradenitis suppurativa refractory to biologic therapy: a …
P Fernandez-Crehuet, S Haselgruber… - Dermatology and …, 2023 - Springer
Introduction Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease. Biologic
drugs have a key role in the long-term anti-inflammatory treatment of moderate to severe …
drugs have a key role in the long-term anti-inflammatory treatment of moderate to severe …
An anti-interleukin-17A monoclonal antibody, ixekizumab, in the treatment of resistant hidradenitis suppurativa: a case series
P Esme, A Botsali, G Akoglu, E Caliskan - Skin Appendage Disorders, 2022 - karger.com
Introduction: Although adalimumab is the only approved biologic for the treatment of
hidradenitis suppurativa (HS), the treatment response may not be satisfactory in all patients …
hidradenitis suppurativa (HS), the treatment response may not be satisfactory in all patients …
Risk of liver dysfunction and non-alcoholic fatty liver diseases in people with hidradenitis suppurativa: A systematic review and meta-analysis of real-world evidences
Background To date, evidences with high evidence-level evaluating the association
between liver diseases and hidradenitis suppurativa was lacking. Given that inconsistency …
between liver diseases and hidradenitis suppurativa was lacking. Given that inconsistency …
The interleukine-17 cytokine family: role in development and progression of spondyloarthritis, current and potential therapeutic inhibitors
A Davydova, Y Kurochkina, V Goncharova… - Biomedicines, 2023 - mdpi.com
Spondyloarthritis (SpA) encompasses a group of chronic inflammatory rheumatic diseases
with a predilection for the spinal and sacroiliac joints, which include axial spondyloarthritis …
with a predilection for the spinal and sacroiliac joints, which include axial spondyloarthritis …
Hidradenitis suppurativa in children and adolescents: an update on pharmacologic treatment options
N Chiang, C Sibbald, R Levy, I Lara-Corrales - Pediatric Drugs, 2023 - Springer
Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin condition that
manifests as painful, deep-seated, inflamed nodules and abscesses in the axillary, groin …
manifests as painful, deep-seated, inflamed nodules and abscesses in the axillary, groin …