Methylthioadenosine phosphorylase deficiency in tumors: A compelling therapeutic target
N Fan, Y Zhang, S Zou - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
The methionine salvage pathway is responsible for recycling sulfur-containing metabolites
to methionine. This salvage pathway has been found to be implicated in cell apoptosis …
to methionine. This salvage pathway has been found to be implicated in cell apoptosis …
Perioperative chemoimmunotherapy with durvalumab for muscle-invasive urothelial carcinoma: primary analysis of the single-arm phase II trial SAKK 06/17
R Cathomas, SI Rothschild, S Hayoz… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE The integration of immunotherapy in the perioperative setting of muscle-invasive
urothelial carcinoma (MIUC) appears promising. SAKK 06/17 investigated the addition of …
urothelial carcinoma (MIUC) appears promising. SAKK 06/17 investigated the addition of …
LC-MS based urine untargeted metabolomic analyses to identify and subdivide urothelial cancer
M Yang, X Liu, X Tang, W Sun, Z Ji - Frontiers in Oncology, 2023 - frontiersin.org
Introduction Urine metabolomics has been a promising technique in the liquid biopsy of
urothelial cancer (UC). The comparison of upper tract urothelial cancer (UTUC), lower tract …
urothelial cancer (UC). The comparison of upper tract urothelial cancer (UTUC), lower tract …
[HTML][HTML] HPV-positive clinically advanced squamous cell carcinoma of the urinary bladder (aBSCC): A comprehensive genomic profiling (CGP) study
GH Ghelani, MB Zerdan, J Jacob, PE Spiess… - … Oncology: Seminars and …, 2023 - Elsevier
Background Advanced bladder squamous cell carcinoma (aBSCC) is an uncommon form of
urinary bladder malignancy when compared with the much higher urothelial carcinoma …
urinary bladder malignancy when compared with the much higher urothelial carcinoma …
Loss of MTAP expression by immunohistochemistry is a surrogate marker for homozygous 9p21. 3 deletion in urothelial carcinoma
T Vlajnic, O Chijioke, L Roma, SS Prince, T Zellweger… - Modern Pathology, 2024 - Elsevier
Homozygous deletion of the chromosomal region 9p21. 3 is common in urothelial carcinoma
(UC) and leads to loss of several genes, including CDKN2A and MTAP, resulting in loss of …
(UC) and leads to loss of several genes, including CDKN2A and MTAP, resulting in loss of …
MTAP protein status is highly concordant with CDKN2A fluorescent in situ hybridization and allows stratification of the luminal subtype in muscle‐invasive bladder …
E Olkhov‐Mitsel, A Oberc, KJ Craddock… - …, 2024 - Wiley Online Library
Aims Loss of heterozygosity in chromosome 9p21, common in urothelial carcinoma (UC),
typically involves deletion of CDKN2A and MTAP genes. MTAP loss is emerging as a …
typically involves deletion of CDKN2A and MTAP genes. MTAP loss is emerging as a …
Metastatic bladder cancer forming a sigmoidorectal fistula after enfortumab vedotin therapy: a case report
S Tamada, D Ikarashi, N Yanagawa… - Frontiers in …, 2023 - frontiersin.org
We report the case of a 68-year-old man who developed a sigmoidorectal fistula after
marked response to enfortumab vedotin for advanced bladder cancer. The patient had …
marked response to enfortumab vedotin for advanced bladder cancer. The patient had …
[PDF][PDF] HPV-positive clinically advanced squamous cell carcinoma of the urinary bladder (aBSCC): A comprehensive genomic profiling (CGP) study
Background: Advanced bladder squamous cell carcinoma (aBSCC) is an uncommon form of
urinary bladder malignancy when compared with the much higher urothelial carcinoma …
urinary bladder malignancy when compared with the much higher urothelial carcinoma …