This review summarizes the brain mechanisms controlling sleep and wakefulness.
Wakefulness promoting systems cause low-voltage, fast activity in the …

Delirium is a neurobehavioral syndrome caused by dysregulation of neuronal activity
secondary to systemic disturbances. Over time, a number of theories have been proposed in …

Acetylcholinesterase is involved in the termination of impulse transmission by rapid
hydrolysis of the neurotransmitter acetylcholine in numerous cholinergic pathways in the …

Autism is a neurodevelopmental disorder characterized by problems with social-
communication, restricted interests and repetitive behavior. A recent and thought-provoking …

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders with
notable factor of dysfunction in cholinergic system. Low ACh level can be observed in the …

As indicated by the profound cognitive impairments caused by cholinergic receptor
antagonists, cholinergic neurotransmission has a vital role in cognitive function, specifically …

Rationale. The developmental history and application of the 5-choice serial reaction time
task (5CSRTT) for measuring effects of drugs and other manipulations on attentional …

Sleep researchers in different disciplines disagree about how fully dreaming can be
explained in terms of brain physiology. Debate has focused on whether REM sleep …

A broad range of evidence regarding the functional organization of the vertebrate brain–
spanning from comparative neurology to experimental psychology and neurophysiology to …

Noradrenergic and cholinergic systems are among the most vulnerable brain systems in
neuropsychiatric diseases of ageing, including Alzheimer's disease, Parkinson's disease …