Combination therapy as a promising way to fight oral cancer

JPN Silva, B Pinto, L Monteiro, PMA Silva, H Bousbaa - Pharmaceutics, 2023 - mdpi.com
Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …

Advantages of the combinatorial molecular targeted therapy of head and neck cancer—A step before anakoinosis-based personalized treatment

R Kleszcz - Cancers, 2023 - mdpi.com
Simple Summary Head and Neck Squamous Cell Carcinoma (HNSCC) is a major threat to
public health around the world. Its occurrence is linked to genetic events and environmental …

Efficacy of combined targeted therapy with PI3K and CDK4/6 or PARP and WEE1 inhibitors in neuroblastoma cell lines

M Lukoseviciute, S Holzhauser… - Oncology …, 2023 - spandidos-publications.com
Neuroblastoma (NB), the most frequent solid extracranial tumor in children, is not always
cured by current aggressive therapies that have notable adverse effects; therefore, novel …

[HTML][HTML] Therapeutic strategy for oncovirus-mediated oral cancer: A comprehensive review

R Thiruvengadam, JH Kim - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Oral cancer is a neoplastic disorder of the oral cavities, including the lips, tongue, buccal
mucosa, and lower and upper gums. Oral cancer assessment entails a multistep process …

Curcumin Alone and Combined With PI3K Inhibitors Elicits Positive Effects on Oropharyngeal Cancer Cell Lines Regardless of HPV Status

M Lukoceviciute, M Zupancic… - Anticancer …, 2024 - ar.iiarjournals.org
Background/Aim: Human papillomavirus positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) is rising in incidence. Compared to HPV-negative (HPV–) OPSCC …

Targeted therapy with PI3K, PARP, and WEE1 inhibitors and radiotherapy in HPV positive and negative tonsillar squamous cell carcinoma cell lines reveals synergy …

K Byskata, M Lukoseviciute, F Tuti, M Zupancic… - Cancers, 2022 - mdpi.com
Simple Summary Human papillomavirus positive tonsillar and base of tongue cancers are
rising in incidence but chemoradiotherapy has not improved survival, so novel treatments …

[HTML][HTML] Impaired DNA double-strand break repair and effective radiosensitization of HPV-negative HNSCC cell lines through combined inhibition of PARP and Wee1

A Oetting, S Christiansen, F Gatzemeier… - Clinical and …, 2023 - Elsevier
Objectives In head and neck squamous cell carcinoma (HNSCC), tumors negative for
Human Papillomavirus (HPV) remain a difficult to treat entity and the morbidity of current …

[PDF][PDF] Combination Therapy as a Promising Way to Fight Oral Cancer. Pharmaceutics 2023, 15, 1653

JPN Silva, B Pinto, L Monteiro, PMA Silva, H Bousbaa - 2023 - academia.edu
Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …

Special Issue “HPV in the Head and Neck Region 2.0”

T Dalianis, C von Buchwald, A Näsman, S Syrjanen - Viruses, 2023 - mdpi.com
Members of the human papillomavirus (HPV) family have been known for causing cancers
and condylomas in the anogenital tract for some time, as reflected by the Nobel Prize in …