Genetic epidemiology of breast cancer in Latin America
The last 10 years witnessed an acceleration of our understanding of what genetic factors
underpin the risk of breast cancer. Rare high-and moderate-penetrance variants such as …
underpin the risk of breast cancer. Rare high-and moderate-penetrance variants such as …
[HTML][HTML] Challenges of diagnostic genomics in Latin America
RM Alvarez-Gomez… - Current Opinion in …, 2021 - Elsevier
Cancer genome sequencing methods have now become essential for diagnostic purposes,
for devising treatment strategies, and for monitoring disease regression and progression …
for devising treatment strategies, and for monitoring disease regression and progression …
Detection of germline variants in Brazilian breast cancer patients using multigene panel testing
RSC Guindalini, DV Viana, JPFW Kitajima… - Scientific reports, 2022 - nature.com
Genetic diversity of germline variants in breast cancer (BC) predisposition genes is
unexplored in miscegenated populations, such those living in Latin America. We evaluated …
unexplored in miscegenated populations, such those living in Latin America. We evaluated …
Germline pathogenic variant prevalence among Latin American and US Hispanic individuals undergoing testing for hereditary breast and ovarian cancer: a cross …
CA Ossa Gomez, MI Achatz, M Hurtado… - JCO Global …, 2022 - ascopubs.org
PURPOSE To report on pathogenic germline variants detected among individuals
undergoing genetic testing for hereditary breast and/or ovarian cancer (HBOC) from Latin …
undergoing genetic testing for hereditary breast and/or ovarian cancer (HBOC) from Latin …
Recommendations for advancing the diagnosis and management of hereditary breast and ovarian cancer in Brazil
PURPOSE The objective of this review was to address the barriers limiting access to genetic
cancer risk assessment and genetic testing for individuals with suspected hereditary breast …
cancer risk assessment and genetic testing for individuals with suspected hereditary breast …
Germline molecular data in hereditary breast cancer in Brazil: Lessons from a large single-center analysis
RL Sandoval, ACR Leite, DM Barbalho, DX Assad… - PloS One, 2021 - journals.plos.org
Brazil is the largest country in South America and the most genetically heterogeneous. The
aim of the present study was to determine the prevalence of germline pathogenic variants …
aim of the present study was to determine the prevalence of germline pathogenic variants …
Frequency of pathogenic germline mutations in early and late onset familial breast cancer patients using multi-gene panel sequencing: an Egyptian study
Background: Precision oncology has been increasingly used in clinical practice and rapidly
evolving in the oncology field. Thus, this study was performed to assess the frequency of …
evolving in the oncology field. Thus, this study was performed to assess the frequency of …
Liquid biopsy as a diagnostic and prognostic tool for women and female dogs with breast Cancer
Simple Summary Breast cancer (BC) has common characteristics in women and female
dogs, such as high recurrence, metastasis, and mortality rate. In both species, BC prognosis …
dogs, such as high recurrence, metastasis, and mortality rate. In both species, BC prognosis …
Genomic ancestry and cancer among Latin Americans
Latin American populations, characterized by intricate admixture patterns resulting from the
intermingling of ancestries from European, Native American (NA) Asian, and African …
intermingling of ancestries from European, Native American (NA) Asian, and African …
A portrait of germline mutation in Brazilian at-risk for hereditary breast cancer
AR de Souza Timoteo, AÉMM Gonçalves… - Breast cancer research …, 2018 - Springer
Purpose Knowledge about the germline mutational spectrum among Brazilian with
hereditary breast and ovarian cancer (HBOC) is limited. Only five studies have performed …
hereditary breast and ovarian cancer (HBOC) is limited. Only five studies have performed …