The application of microbes to valorize aromatic compounds derived from the abundant
plant biopolymer lignin is a rapidly developing area of research that may ultimately enable …

Carotenoid cleavage dioxygenases (CCDs) comprise a superfamily of mononuclear non-
heme iron proteins that catalyze the oxygenolytic fission of alkene bonds in carotenoids to …

The carotenoids are terpenoid fat-soluble pigments produced by plants, algae, and several
bacteria and fungi. They are ubiquitous components of animal diets. Carotenoid cleavage …

Aromatic hydrocarbons (AH) are widely distributed in nature, and many of them have been
reported as relevant environmental pollutants and valuable carbon sources for different …

Double bonds are prevalent in various substrates and renewable feedstocks, and their
cleavage typically necessitates harsh reaction conditions involving high temperatures …

Lignostilbene-α, β-dioxygenase A (LsdA) from the bacterium Sphingomonas paucimobilis
TMY1009 is a nonheme iron oxygenase that catalyzes the cleavage of lignostilbene, a …

The enzymatic biosynthesis of fragrance molecules from lignin fragments is an important
reaction in biotechnology for the sustainable production of fine chemicals. In this work we …

Vanillin has many applications in industries. Isoeugenol monooxygenase (IEM) can catalyze
the oxidation of isoeugenol to vanillin in the presence of oxygen under mild conditions …

Synthesis of β‐ionone in microbial cell factories is limited by the efficiency of carotenoid
cleavage dioxygenases (CCDs). To obtain genes responsible for specific cleavage of …

In this article, we report sterically-controlled iron sites based on non-chelating bulky
imidazole ligands. Adding 6 equiv. of 1, 2-dimethylimidazole (1, 2-Me 2 Im) to Fe (OTf) 2⋅ …