Lower urinary tract development and disease

HM Rasouly, W Lu - Wiley Interdisciplinary Reviews: Systems …, 2013 - Wiley Online Library
Congenital anomalies of the lower urinary tract (CALUT) are a family of birth defects of the
ureter, the bladder, and the urethra. CALUT includes ureteral anomaliesc such as congenital …

Multidisciplinary approaches for elucidating genetics and molecular pathogenesis of urinary tract malformations

K Khan, DF Ahram, YP Liu, R Westland… - Kidney international, 2022 - Elsevier
Advances in clinical diagnostics and molecular tools have improved our understanding of
the genetically heterogeneous causes underlying congenital anomalies of kidney and …

Update from a cohort study for birth defects in Hunan Province, China, 2010–2020

X Zhou, S Cai, H Wang, J Fang, J Gao, H Kuang… - Scientific reports, 2023 - nature.com
To define the relationship between sex, residence, maternal age, and a broad range of birth
defects by conducting a comprehensive cross-analysis based on up-to-date data. Data were …

Contemporary epidemiological trends in complex congenital genitourinary anomalies

JC Lloyd, JS Wiener, PC Gargollo, BA Inman… - The Journal of …, 2013 - auajournals.org
Purpose: Anecdotal evidence suggests that complex congenital genitourinary anomalies are
occurring less frequently. However, few epidemiological studies are available to confirm or …

Congenital disorders of the human urinary tract: recent insights from genetic and molecular studies

AS Woolf, FM Lopes, P Ranjzad, NA Roberts - Frontiers in pediatrics, 2019 - frontiersin.org
The urinary tract comprises the renal pelvis, the ureter, the urinary bladder, and the urethra.
The tract acts as a functional unit, first propelling urine from the kidney to the bladder, then …

Cloacal exstrophy: an epidemiologic study from the International Clearinghouse for Birth Defects Surveillance and Research

ML Feldkamp, LD Botto, E Amar… - American Journal of …, 2011 - Wiley Online Library
Cloacal exstrophy presents as a complex abdominal wall defect thought to result from a
mesodermal abnormality. Anatomically, its main components are Omphalocele, bladder …

Development of the ventral body wall in the human embryo

HK Mekonen, JPJM Hikspoors, G Mommen… - Journal of …, 2015 - Wiley Online Library
Migratory failure of somitic cells is the commonest explanation for ventral body wall defects.
However, the embryo increases~ 25‐fold in volume in the period that the ventral body wall …

Complex abdominal wall defects: appearances at prenatal imaging

R Pakdaman, PJ Woodward, A Kennedy - Radiographics, 2015 - pubs.rsna.org
Abdominal wall defects are a complex group of anomalies, and many are incorrectly
diagnosed. Evaluation of the defect relative to the umbilical cord insertion site is …

[HTML][HTML] Laparoscopic inguinal hernia repair in bladder exstrophy, a new modified solution to an old problem: a cohort study

H Taher, A Elboraie, A Fares, S Tawfiq… - International Journal of …, 2022 - Elsevier
Purpose Open inguinal hernia repair in children with bladder exstrophy is challenging and
associated with a high recurrence rate (15%–22%). We report our initial experience with …

[HTML][HTML] In vivo knockdown of Brachyury results in skeletal defects and urorectal malformations resembling caudal regression syndrome

T Pennimpede, J Proske, A König, JA Vidigal… - Developmental …, 2012 - Elsevier
The T-box transcription factor BRACHYURY (T) is a key regulator of mesoderm formation
during early development. Complete loss of T has been shown to lead to embryonic lethality …