Living in a hypoxic world: A review of the impacts of hypoxia on aquaculture

Y Zhan, B Ning, J Sun, Y Chang - Marine Pollution Bulletin, 2023 - Elsevier
Hypoxia is a harmful result of anthropogenic climate change. With the expansion of global
low-oxygen zones (LOZs), many organisms have faced unprecedented challenges affecting …

The asparagine hydroxylase FIH: a unique oxygen sensor

YL Volkova, C Pickel, AE Jucht, RH Wenger… - Antioxidants & redox …, 2022 - liebertpub.com
Significance: Limited oxygen availability (hypoxia) commonly occurs in a range of
physiological and pathophysiological conditions, including embryonic development …

[HTML][HTML] Exosomes from adipose-derived stem cells alleviate myocardial infarction via microRNA-31/FIH1/HIF-1α pathway

D Zhu, Y Wang, M Thomas, KA McLaughlin… - Journal of molecular and …, 2022 - Elsevier
Our previous study has revealed that exosomes from adipose-derived stem cells (ASCs)
promote angiogenesis in subcutaneously transplanted gels by delivery of microRNA-31 …

Vegfaa instructs cardiac muscle hyperplasia in adult zebrafish

R Karra, MJ Foglia, WY Choi… - Proceedings of the …, 2018 - National Acad Sciences
During heart development and regeneration, coronary vascularization is tightly coupled with
cardiac growth. Although inhibiting vascularization causes defects in the innate regenerative …

Effects of acute hypoxia and reoxygenation on oxygen sensors, respiratory metabolism, oxidative stress, and apoptosis in hybrid yellow catfish “Huangyou-1”

X Pei, M Chu, P Tang, H Zhang, X Zhang… - Fish Physiology and …, 2021 - Springer
The regulation mechanism of the hybrid yellow catfish “Huangyou-1” was assessed under
conditions of hypoxia and reoxygenation by examination of oxygen sensors and by …

Nanoplastics exposure induces vascular malformation by interfering with the VEGFA/VEGFR pathway in zebrafish (Danio rerio)

L Dai, J Luo, M Feng, M Wang, J Zhang, X Cao, X Yang… - Chemosphere, 2023 - Elsevier
The widespread accumulation and adverse effects of nanoplastics (NPs) are a growing
concern for environmental and human health. However, the potential toxicological effects of …

Exploring the HIFs, buts and maybes of hypoxia signalling in disease: lessons from zebrafish models

PM Elks, SA Renshaw, AH Meijer… - Disease models & …, 2015 - journals.biologists.com
ABSTRACT A low level of tissue oxygen (hypoxia) is a physiological feature of a wide range
of diseases, from cancer to infection. Cellular hypoxia is sensed by oxygen-sensitive …

The small members of the JMJD protein family: Enzymatic jewels or jinxes?

S Oh, S Shin, R Janknecht - Biochimica et Biophysica Acta (BBA)-Reviews …, 2019 - Elsevier
Jumonji C domain-containing (JMJD) proteins are mostly epigenetic regulators that
demethylate histones. However, a hitherto neglected subfamily of JMJD proteins …

MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis

X Wang, CC Ling, L Li, Y Qin, J Qi, X Liu… - Cardiovascular …, 2016 - academic.oup.com
Abstract Aims MicroRNA-10 (miR-10) was originally shown to regulate angiogenesis by
directly modulating the levels of membrane-bound fms-related tyrosine kinase 1 (mflt1) and …

Oncolytic HSV–Infected Glioma Cells Activate NOTCH in Adjacent Tumor Cells Sensitizing Tumors to Gamma Secretase Inhibition

Y Otani, JY Yoo, S Chao, J Liu, AC Jaime-Ramirez… - Clinical Cancer …, 2020 - AACR
Purpose: To examine the effect of oncolytic herpes simplex virus (oHSV) on NOTCH
signaling in central nervous system tumors. Experimental Design: Bioluminescence …