Histone variants provide versatility in the basic unit of chromatin, helping to define dynamic
landscapes and cell fates. Maintaining genome integrity is paramount for the cell, and it is …

How different intrinsic sequence variations and regulatory modifications of histones combine
in nucleosomes remain unclear. To test the importance of histone variants in the …

The evolutionarily conserved HIRA/Hir histone chaperone complex and ASF1a/Asf1 co-
chaperone cooperate to deposit histone (H3/H4) 2 tetramers on DNA for replication …

Abstract The Alternative Lengthening of Telomeres (ALT) pathway is a homology-directed
repair (HDR) mechanism of telomere extension that enables the proliferation of several …

Complex organisms require a single genome to instruct diverse cell lineages while
simultaneously allowing for rapid and selective cellular responses to environmental signals …

L'Adénovirus est un virus à ADN double brin qui est utilisé comme vecteur vaccinal. Son
génome est très compacté à l'intérieur de la particule virale et il est organisé en chromatine …

Genom polyomavirů má podobu kruhové dsDNA (double-stranded DNA), která je ve
virionech a během celého replikačního cyklu v komplexu s buněčnými histony. Komplex …

All the cells of an organism contain the same genome. However, each cell expresses only a
minor fraction of its potential and, in particular, the genes encoding the proteins necessary …

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