Runs of homozygosity: current knowledge and applications in livestock

E Peripolli, DP Munari, M Silva, ALF Lima… - Animal …, 2017 - Wiley Online Library
This review presents a broader approach to the implementation and study of runs of
homozygosity (ROH) in animal populations, focusing on identifying and characterizing ROH …

[HTML][HTML] Genomics and genetics in the biology of adaptation to exercise

C Bouchard, T Rankinen… - Comprehensive Physiology, 2011 - ncbi.nlm.nih.gov
This chapter is devoted to the role of genetic variation and gene-exercise interactions in the
biology of adaptation to exercise. There is evidence from genetic epidemiology research that …

[HTML][HTML] Integrating common and rare genetic variation in diverse human populations

International HapMap 3 Consortium - Nature, 2010 - ncbi.nlm.nih.gov
Despite great progress in identifying genetic variants that influence human disease, most
inherited risk remains unexplained. A more complete understanding requires genome-wide …

[HTML][HTML] Genomic scan of selective sweeps in thin and fat tail sheep breeds for identifying of candidate regions associated with fat deposition

MH Moradi, A Nejati-Javaremi, M Moradi-Shahrbabak… - BMC genetics, 2012 - Springer
Background Identification of genomic regions that have been targets of selection for
phenotypic traits is one of the most important and challenging areas of research in animal …

[HTML][HTML] Genome-wide analysis reveals selection for important traits in domestic horse breeds

JL Petersen, JR Mickelson, AK Rendahl… - PLoS …, 2013 - journals.plos.org
Intense selective pressures applied over short evolutionary time have resulted in
homogeneity within, but substantial variation among, horse breeds. Utilizing this population …

[HTML][HTML] Detection of selection signatures in dairy and beef cattle using high-density genomic information

F Zhao, S McParland, F Kearney, L Du… - Genetics Selection …, 2015 - Springer
Background Artificial selection for economically important traits in cattle is expected to have
left distinctive selection signatures on the genome. Access to high-density genotypes …

Adaptations to climate-mediated selective pressures in sheep

FH Lv, S Agha, J Kantanen, L Colli… - Molecular biology …, 2014 - academic.oup.com
Following domestication, sheep (Ovis aries) have become essential farmed animals across
the world through adaptation to a diverse range of environments and varied production …

A critical assessment of storytelling: gene ontology categories and the importance of validating genomic scans

P Pavlidis, JD Jensen, W Stephan… - Molecular biology and …, 2012 - academic.oup.com
In the age of whole-genome population genetics, so-called genomic scan studies often
conclude with a long list of putatively selected loci. These lists are then further scrutinized to …

[HTML][HTML] A Sequence Polymorphism in MSTN Predicts Sprinting Ability and Racing Stamina in Thoroughbred Horses

EW Hill, J Gu, SS Eivers, RG Fonseca, BA McGivney… - PloS one, 2010 - journals.plos.org
Variants of the MSTN gene encoding myostatin are associated with muscle hypertrophy
phenotypes in a range of mammalian species, most notably cattle, dogs, mice, and humans …

Fifteen years of genomewide scans for selection: trends, lessons and unaddressed genetic sources of complication

RJ Haasl, BA Payseur - Molecular ecology, 2016 - Wiley Online Library
Genomewide scans for natural selection (GWSS) have become increasingly common over
the last 15 years due to increased availability of genome‐scale genetic data. Here, we report …