Non-protein-coding sequences increasingly dominate the genomes of multicellular
organisms as their complexity increases, in contrast to protein-coding genes, which remain …

The autism spectrum disorders (ASD) comprise a complex group of behaviorally related
disorders that are primarily genetic in origin. Involvement of epigenetic regulatory …

A large portion of the eukaryotic genome is transcribed as noncoding RNAs (ncRNAs).
While once thought of primarily as “junk,” recent studies indicate that a large number of …

BACKGROUND Genomic imprinting is an epigenetic gene regulatory mechanism; disruption
of this process during early embryonic development can have major consequences on both …

Silver–Russell syndrome (SRS MIM180860) is a disorder characterised by intrauterine
and/or postnatal growth restriction and typical facies. However, the clinical picture is …

The identification of human sequence polymorphisms that regulate gene expression is key
to understanding human genetic diseases. We report a survey of human genes that …

Overexpression of the imprinted insulin-like growth factor-II (IGF2) is a prominent
characteristic of gynecologic malignancies. The purpose of this study was to determine …

OBJECTIVE: To study the methylation imprinting marks of two oppositely imprinted genes,
H19 and MEST/PEG1, in human testicular spermatozoa from azoospermic patients with …

It is now becoming evident that the variety of noncoding RNA (ncRNA) molecules play
important roles in many cellular processes and they are not just mere intermediates in …

FOXP2 (forkhead box P2) was the first gene characterized in which a mutation affects
human speech and language abilities. A common developmental language disorder …