Ethical issues when using digital biomarkers and artificial intelligence for the early detection of dementia

E Ford, R Milne, K Curlewis - Wiley Interdisciplinary Reviews …, 2023 - Wiley Online Library
Dementia poses a growing challenge for health services but remains stigmatized and under‐
recognized. Digital technologies to aid the earlier detection of dementia are approaching …

Ethical aspects of prodromal synucleinopathy prognostic counseling

A Stefani, J Mozersky, V Kotagal, B Högl… - Seminars in …, 2023 - thieme-connect.com
Alpha-synucleinopathies can be identified in their prodromal phase, raising several ethical
issues. In this review, we first provide definitions of prodromal α-synucleinopathies and …

Mild cognitive impairment in relation to Alzheimer's disease: An investigation of principles, classifications, ethics, and problems

J Lee - Neuroethics, 2023 - Springer
Abstract Mild Cognitive Impairment (MCI) is a diagnostic category indicating cognitive
impairment which does not meet diagnostic criteria for dementia such as Alzheimer's …

Knowledge of risk and protective factors for dementia in older German adults A population-based survey on risk and protective factors for dementia and internet-based …

AE Zülke, M Luppa, S Köhler, SG Riedel-Heller - PLoS One, 2022 - journals.plos.org
Background Evidence on potentially modifiable risk factors for dementia is accumulating
rapidly, including eg physical inactivity, hypertension, or diabetes. It is unclear to what extent …

Barriers and facilitators to the adoption of electronic clinical decision support systems: a qualitative interview study with UK general practitioners

E Ford, N Edelman, L Somers, D Shrewsbury… - BMC medical informatics …, 2021 - Springer
Background Well-established electronic data capture in UK general practice means that
algorithms, developed on patient data, can be used for automated clinical decision support …

European Academy of Neurology/European Alzheimer's Disease Consortium position statement on diagnostic disclosure, biomarker counseling, and management of …

KS Frederiksen, TR Nielsen, B Winblad… - European Journal of …, 2021 - Wiley Online Library
Background and purpose Careful counseling through the diagnostic process and adequate
postdiagnostic support in patients with mild cognitive impairment (MCI) is important …

Automated detection of patients with dementia whose symptoms have been identified in primary care but have no formal diagnosis: a retrospective case–control study …

E Ford, J Sheppard, S Oliver, P Rooney, S Banerjee… - BMJ open, 2021 - bmjopen.bmj.com
Objectives UK statistics suggest only two-thirds of patients with dementia get a diagnosis
recorded in primary care. General practitioners (GPs) report barriers to formally diagnosing …

Attitudes towards prediction and early diagnosis of late-onset dementia: a comparison of tested persons and family caregivers

JL Lohmeyer, Z Alpinar-Sencan… - Aging & Mental …, 2021 - Taylor & Francis
Background: The focus on early detection of dementia and Mild Cognitive Impairment (MCI)
diagnosis has entered the clinics' daily routine. However, there exist epistemic uncertainty …

Impact of sharing Alzheimer's disease biomarkers with individuals without dementia: a systematic review and meta‐analysis of empirical data

J van der Schaar, LNC Visser, JCF Ket… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction We conducted a systematic literature review and meta‐analysis of empirical
evidence on expected and experienced implications of sharing Alzheimer's disease (AD) …

Ethical implications of Alzheimer's disease prediction in asymptomatic individuals through artificial intelligence

F Ursin, C Timmermann, F Steger - Diagnostics, 2021 - mdpi.com
Biomarker-based predictive tests for subjectively asymptomatic Alzheimer's disease (AD)
are utilized in research today. Novel applications of artificial intelligence (AI) promise to …