Potential of nanoparticles as permeation enhancers and targeted delivery options for skin: Advantages and disadvantages

P Ghasemiyeh… - Drug design, development …, 2020 - Taylor & Francis
The topical route of administration has many advantages for the treatment of various skin
disorders as well as cosmeceutical purposes. This route bypasses hepatic first-pass effect …

Topical and transdermal drug delivery: from simple potions to smart technologies

HAE Benson, JE Grice, Y Mohammed… - Current drug …, 2019 - ingentaconnect.com
This overview on skin delivery considers the evolution of the principles of percutaneous
absorption and skin products from ancient times to today. Over the ages, it has been …

Nanoemulsion: A review on mechanisms for the transdermal delivery of hydrophobic and hydrophilic drugs

DS Shaker, RAH Ishak, A Ghoneim… - Scientia Pharmaceutica, 2019 - mdpi.com
Nanoemulsions (NEs) are colloidal dispersions of two immiscible liquids, oil and water, in
which one is dispersed in the other with the aid of a surfactant/co-surfactant mixture, either …

Preparation of a novel curcumin nanoemulsion by ultrasonication and its comparative effects in wound healing and the treatment of inflammation

N Ahmad, R Ahmad, A Al-Qudaihi, SE Alaseel, IZ Fita… - RSC …, 2019 - pubs.rsc.org
The aim of this study was to develop and evaluate a curcumin (Cur) nanoemulsion (NE) and
enhance transdermal drug delivery. The comparative effects of Cur-NE were evaluated in …

Topical and cutaneous delivery using nanosystems

MS Roberts, Y Mohammed, MN Pastore… - Journal of controlled …, 2017 - Elsevier
The goal of topical and cutaneous delivery is to deliver therapeutic and other substances to
a desired target site in the skin at appropriate doses to achieve a safe and efficacious …

Topical nano and microemulsions for skin delivery

CMRR Nastiti, T Ponto, E Abd, JE Grice, HAE Benson… - Pharmaceutics, 2017 - mdpi.com
Nanosystems such as microemulsions (ME) and nanoemulsions (NE) offer considerable
opportunities for targeted drug delivery to and via the skin. ME and NE are stable colloidal …

Natural Ingredients of Transdermal Drug Delivery Systems as Permeation Enhancers of Active Substances through the Stratum Corneum

N Schafer, R Balwierz, P Biernat… - Molecular …, 2023 - ACS Publications
In recent years, significant progress has been made in transdermal drug delivery systems,
but there is still a search for enhancers that can improve the absorption of active substances …

Nanoemulsion loaded polymeric hydrogel for topical delivery of curcumin in psoriasis

MS Algahtani, MZ Ahmad, J Ahmad - Journal of Drug Delivery Science and …, 2020 - Elsevier
Curcumin is a natural compound with multiple molecular targets that causes inhibition of
factors involved in pathogenesis of psoriasis but low solubility and poor skin penetrability …

Saponins as natural emulsifiers for nanoemulsions

TB Schreiner, MM Dias, MF Barreiro… - Journal of agricultural …, 2022 - ACS Publications
The awareness of sustainability approaches has focused attention on replacing synthetic
emulsifiers with natural alternatives when formulating nanoemulsions. In this context, a …

Systematic review on the effectiveness of essential and carrier oils as skin penetration enhancers in pharmaceutical formulations

B Alhasso, MU Ghori, BR Conway - Scientia Pharmaceutica, 2022 - mdpi.com
Oils, including essential oils and their constituents, are widely reported to have penetration
enhancement activity and have been incorporated into a wide range of pharmaceutical …