Yeast peroxisomes: structure, functions and biotechnological opportunities

AA Sibirny - FEMS yeast research, 2016 - academic.oup.com
Peroxisomes are ubiquitous organelles found in most eukaryotic cells. In yeasts,
peroxisomes play important roles in cell metabolism, especially in different catabolic …

[HTML][HTML] The type-2 peroxisomal targeting signal

M Kunze - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
The type-2 peroxisomal targeting signal (PTS2) is one of two peptide motifs destining
soluble proteins for peroxisomes. This signal acts as amphiphilic α-helix exposing the side …

Engineering Yarrowia lipolytica as a platform for synthesis of drop-in transportation fuels and oleochemicals

P Xu, K Qiao, WS Ahn… - Proceedings of the …, 2016 - National Acad Sciences
Harnessing lipogenic pathways and rewiring acyl-CoA and acyl-ACP (acyl carrier protein)
metabolism in Yarrowia lipolytica hold great potential for cost-efficient production of diesel …

Harnessing yeast peroxisomes for biosynthesis of fatty-acid-derived biofuels and chemicals with relieved side-pathway competition

YJ Zhou, NA Buijs, Z Zhu, DO Gómez… - Journal of the …, 2016 - ACS Publications
Establishing efficient synthetic pathways for microbial production of biochemicals is often
hampered by competing pathways and/or insufficient precursor supply …

Compartmentalized biosynthesis of mycophenolic acid

W Zhang, L Du, Z Qu, X Zhang, F Li… - Proceedings of the …, 2019 - National Acad Sciences
Mycophenolic acid (MPA) from filamentous fungi is the first natural product antibiotic to be
isolated and crystallized, and a first-line immunosuppressive drug for organ transplantations …

Engineering sub-organelles of a diploid Saccharomyces cerevisiae to enhance the production of 7-dehydrocholesterol

K Bi, W Wang, D Tang, Z Shi, S Tian, L Huang… - Metabolic …, 2024 - Elsevier
Dehydrocholesterol (7-DHC) is widely present in various organisms and is an important
precursor of vitamin D 3. Despite significant improvements in the biosynthesis of 7-DHC, it …

Peroxisomes in parasitic protists

T Gabaldón, ML Ginger, PAM Michels - Molecular and biochemical …, 2016 - Elsevier
Representatives of all major lineages of eukaryotes contain peroxisomes with similar
morphology and mode of biogenesis, indicating a monophyletic origin of the organelles …

Contribution of peroxisomal docking machinery to mycotoxin biosynthesis, pathogenicity and pexophagy in the plant pathogenic fungus Fusarium graminearum

Y Chen, S Zheng, Z Ju, C Zhang, G Tang… - Environmental …, 2018 - Wiley Online Library
Peroxisomal proliferation is highly stimulated during the biosynthesis of mycotoxins and
plant infection by Fusarium graminearum. Currently, the functions of the peroxisome in these …

Dynamic regulation of peroxisomes and mitochondria during fungal development

R Navarro-Espíndola, F Suaste-Olmos… - Journal of Fungi, 2020 - mdpi.com
Peroxisomes and mitochondria are organelles that perform major functions in the cell and
whose activity is very closely associated. In fungi, the function of these organelles is critical …

Peroxisomes implicated in the biosynthesis of siderophores and biotin, cell wall integrity, autophagy, and response to hydrogen peroxide in the citrus pathogenic …

PC Wu, YK Chen, JI Yago, KR Chung - Frontiers in microbiology, 2021 - frontiersin.org
Little is known about the roles of peroxisomes in the necrotrophic fungal plant pathogens. In
the present study, a Pex6 gene encoding an ATPase-associated protein was characterized …