Paternal DNA packaging in spermatozoa: more than the sum of its parts? DNA, histones, protamines and epigenetics

D Miller, M Brinkworth, D Iles - Reproduction, 2010 - rep.bioscientifica.com
Testicular tumours in dogs are of Sertoli cell, Leydig cell or germinal origin and mixed
tumours are also frequently observed. The cellular components of mixed tumours are …

Basic concepts of epigenetics: impact of environmental signals on gene expression

EA Mazzio, KFA Soliman - Epigenetics, 2012 - Taylor & Francis
Through epigenetic modifications, specific long-term phenotypic consequences can arise
from environmental influence on slowly evolving genomic DNA. Heritable epigenetic …

HIV-1 transcription and latency: an update

C Van Lint, S Bouchat, A Marcello - Retrovirology, 2013 - Springer
Combination antiretroviral therapy, despite being potent and life-prolonging, is not curative
and does not eradicate HIV-1 infection since interruption of treatment inevitably results in a …

[HTML][HTML] Basic concepts of epigenetics

M Inbar-Feigenberg, S Choufani, DT Butcher… - Fertility and sterility, 2013 - Elsevier
Several types of epigenetic marks facilitate the complex patterning required for normal
human development. These epigenetic marks include DNA methylation at CpG …

Fetal programming: link between early nutrition, DNA methylation, and complex diseases

A Chmurzynska - Nutrition reviews, 2010 - academic.oup.com
Complex traits, including those involved in diet-related diseases, are determined by multiple
genes and environmental influences. Factors influencing the development of complex traits …

DNA methylation: an introduction to the biology and the disease-associated changes of a promising biomarker

J Tost - Molecular biotechnology, 2010 - Springer
DNA methylation occurring on the 5 position of the pyrimidine ring of cytosines in the context
of the dinucleotide sequence CpG forms one of the multiple layers of epigenetic …

Developmental programming of early brain and behaviour development and mental health: a conceptual framework

BRH Van den Bergh - Developmental Medicine & Child …, 2011 - Wiley Online Library
The Developmental Origins of Health and Disease (DOHaD) hypothesis studies the short‐
and long‐term consequences of the conditions of the developmental environment for …

Molecular control of HIV-1 postintegration latency: implications for the development of new therapeutic strategies

L Colin, C Van Lint - Retrovirology, 2009 - Springer
The persistence of HIV-1 latent reservoirs represents a major barrier to virus eradication in
infected patients under HAART since interruption of the treatment inevitably leads to a …

Butyrate histone deacetylase inhibitors

K Steliou, MS Boosalis, SP Perrine… - BioResearch open …, 2012 - liebertpub.com
In addition to being a part of the metabolic fatty acid fuel cycle, butyrate is also capable of
inducing growth arrest in a variety of normal cell types and senescence-like phenotypes in …

Advances in microbial culturing conditions to activate silent biosynthetic gene clusters for novel metabolite production

HA Tomm, L Ucciferri, AC Ross - Journal of Industrial …, 2019 - academic.oup.com
Natural products (NPs) produced by bacteria and fungi are often used as therapeutic agents
due to their complex structures and wide range of bioactivities. Enzymes that build NPs are …