Immunoinformatics and vaccine development: an overview

AN Oli, WO Obialor, MO Ifeanyichukwu… - ImmunoTargets and …, 2020 - Taylor & Francis
The use of vaccines have resulted in a remarkable improvement in global health. It has
saved several lives, reduced treatment costs and raised the quality of animal and human …

Unraveling the potential of M13 phages in biomedicine: Advancing drug nanodelivery and gene therapy

M Fadaie, H Dianat-Moghadam, E Ghafouri… - Environmental …, 2023 - Elsevier
M13 phages possessing filamentous phage genomes offer the benefits of selective display
of molecular moieties and delivery of therapeutic agent payloads with a tolerable safety …

Multi-epitope based vaccine against yellow fever virus applying immunoinformatics approaches

SFO Tosta, MS Passos, R Kato, Á Salgado… - Journal of …, 2021 - Taylor & Francis
Yellow fever disease is considered a re-emerging major health issue which has caused
recent outbreaks with a high number of deaths. Tropical countries, mainly African and South …

Immunoinformatics driven construction of multi-epitope vaccine candidate against Ascaris lumbricoides using its entire immunogenic epitopes

R Kaur, N Arora, SS Rawat, AK Keshri… - Expert Review of …, 2021 - Taylor & Francis
Objective Ascaris lumbricoides infects 80 million people per year, causing malnutrition,
stunted growth of children etc., but there is no vaccine available against it. We aimed to …

Development of multi-epitope chimeric vaccine against Taenia solium by exploring its proteome: an in silico approach

R Kaur, N Arora, MA Jamakhani, S Malik… - Expert review of …, 2020 - Taylor & Francis
Objective: Taenia solium is a neglected tropical disease; larvae of this parasite infect central
nervous system ie Neurocysticercosis, and adults mature and survive into intestine ie …

[HTML][HTML] Leveraging the wheat germ cell-free protein synthesis system to accelerate malaria vaccine development

BN Kanoi, H Nagaoka, M Morita, T Tsuboi… - Parasitology …, 2021 - Elsevier
Vaccines against infectious diseases have had great successes in the history of public
health. Major breakthroughs have occurred in the development of vaccine-based …

A cutting-edge immunoinformatics approach for design of multi-epitope oral vaccine against dreadful human malaria

M Pritam, G Singh, S Swaroop, AK Singh… - International Journal of …, 2020 - Elsevier
Human malaria is a pathogenic disease mainly caused by Plasmodium falciparum, which
was responsible for about 405,000 deaths globally in the year 2018. To date, several …

Tracking the pipeline: immunoinformatics and the COVID-19 vaccine design

S Rezaei, Y Sefidbakht… - Briefings in Bioinformatics, 2021 - academic.oup.com
With the onset of the COVID-19 pandemic, the amount of data on genomic and proteomic
sequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) stored in …

Screening and characterization of hypothetical proteins of Plasmodium falciparum as novel vaccine candidates in the fight against malaria using reverse vaccinology

C Aguttu, BA Okech, A Mukisa, GW Lubega - Journal of Genetic …, 2021 - Elsevier
Background Plasmodium falciparum is the most deadly and leading cause of morbidity and
mortality in Africa. About 90% of all malaria deaths in the world today occur in Sub-Saharan …

Vaccine for a neglected tropical disease Taenia solium cysticercosis: fight for eradication against all odds

R Kaur, N Arora, SS Rawat, AK Keshri… - Expert Review of …, 2021 - Taylor & Francis
Introduction Taenia solium infection is among the 17 most neglected tropical diseases
identified by World Health Organization and to be eradicated by 2030. This parasite infects …