Mesenchymal stem cells for neurological disorders
A Andrzejewska, S Dabrowska, B Lukomska… - Advanced …, 2021 - Wiley Online Library
Neurological disorders are becoming a growing burden as society ages, and there is a
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …
compelling need to address this spiraling problem. Stem cell‐based regenerative medicine …
Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases
S Ji, M Xiong, H Chen, Y Liu, L Zhou, Y Hong… - … and Targeted Therapy, 2023 - nature.com
The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …
Microglia and astrocytes in Alzheimer's disease: implications for therapy
M Fakhoury - Current neuropharmacology, 2018 - ingentaconnect.com
Background: Alzheimer's disease (AD) is a complex neurodegenerative disorder
characterized by the progressive loss of neurons, which typically leads to severe …
characterized by the progressive loss of neurons, which typically leads to severe …
RVG-modified exosomes derived from mesenchymal stem cells rescue memory deficits by regulating inflammatory responses in a mouse model of Alzheimer's …
G Cui, H Guo, H Li, Y Zhai, Z Gong, J Wu, J Liu… - Immunity & …, 2019 - Springer
Background Exosomes are lipid-bilayer enclosed nano-sized vesicles that transfer
functional cellular proteins, mRNA and miRNAs. Mesenchymal stem cells (MSCs) derived …
functional cellular proteins, mRNA and miRNAs. Mesenchymal stem cells (MSCs) derived …
Intranasal delivery of mesenchymal stem cell-derived extracellular vesicles exerts immunomodulatory and neuroprotective effects in a 3xTg model of Alzheimer's …
M Losurdo, M Pedrazzoli, C D'Agostino… - Stem cells …, 2020 - academic.oup.com
The critical role of neuroinflammation in favoring and accelerating the pathogenic process in
Alzheimer's disease (AD) increased the need to target the cerebral innate immune cells as a …
Alzheimer's disease (AD) increased the need to target the cerebral innate immune cells as a …
Alzheimer's disease, dementia, and stem cell therapy
T Duncan, M Valenzuela - Stem cell research & therapy, 2017 - Springer
Alzheimer's disease (AD) represents arguably the most significant social, economic, and
medical crisis of our time. Characterized by progressive neurodegenerative pathology, AD is …
medical crisis of our time. Characterized by progressive neurodegenerative pathology, AD is …
[HTML][HTML] Stem cell therapy for Alzheimer's disease
XY Liu, LP Yang, L Zhao - World journal of stem cells, 2020 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by
memory loss and cognitive impairment. It is caused by synaptic failure and excessive …
memory loss and cognitive impairment. It is caused by synaptic failure and excessive …
MSCs vs. iPSCs: Potential in therapeutic applications
K Thanaskody, AS Jusop, GJ Tye… - Frontiers in Cell and …, 2022 - frontiersin.org
Over the past 2 decades, mesenchymal stem cells (MSCs) have attracted a lot of interest as
a unique therapeutic approach for a variety of diseases. MSCs are capable of self-renewal …
a unique therapeutic approach for a variety of diseases. MSCs are capable of self-renewal …
Factors that influence adult neurogenesis as potential therapy
Adult neurogenesis involves persistent proliferative neuroprogenitor populations that reside
within distinct regions of the brain. This phenomenon was first described over 50 years ago …
within distinct regions of the brain. This phenomenon was first described over 50 years ago …
Innovative therapy for Alzheimer's disease-with focus on biodelivery of NGF
S Mitra, H Behbahani, M Eriksdotter - Frontiers in neuroscience, 2019 - frontiersin.org
Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with
abnormal protein modification, inflammation and memory impairment. Aggregated amyloid …
abnormal protein modification, inflammation and memory impairment. Aggregated amyloid …