Obesity is increasingly prevalent and is associated with substantial cardiovascular risk.
Adipose tissue distribution and morphology play a key role in determining the degree of …

Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …

Perivascular adipose tissue (PVAT) is an additional special type of adipose tissue
surrounding blood vessels. Under physiological conditions, PVAT plays a significant role in …

The mechanisms by which exercise benefits patients with non-alcoholic fatty liver disease
(NAFLD), the most common liver disease worldwide, remain poorly understood. A non …

Cancer-associated cachexia (CAC) is a hypermetabolic syndrome characterized by
unintended weight loss due to the atrophy of adipose tissue and skeletal muscle. A …

Obesity is characterized by chronic and low-grade systemic inflammation, an increase of
adipose tissue, hypertrophy, and hyperplasia of adipocytes. Adipose tissues can be …

Emerging evidence suggests that n-3 polyunsaturated fatty acids (PUFA) promote brown
adipose tissue thermogenesis. However, the underlying mechanisms remain elusive. Here …

We are facing a revival of the strategy to counteract obesity and associated metabolic
disorders by inducing thermogenesis mediated by mitochondrial uncoupling protein-1 …

Perivascular adipose tissue (PVAT) is a specialized type of adipose tissue that surrounds
most mammalian blood vessels. PVAT is a metabolically active, endocrine organ capable of …

Key points• Perinatal maternal high‐fat diet changes milk composition, resulting in obesity
and hyperglycaemia in male offspring at weaning.• Offspring obesity is associated with …