Designing microbial cell factories for the production of chemicals

JS Cho, GB Kim, H Eun, CW Moon, SY Lee - Jacs Au, 2022 - ACS Publications
The sustainable production of chemicals from renewable, nonedible biomass has emerged
as an essential alternative to address pressing environmental issues arising from our heavy …

Systems metabolic engineering of microorganisms for food and cosmetics production

KR Choi, SY Lee - Nature Reviews Bioengineering, 2023 - nature.com
The demand for sustainable and environmentally friendly sources of foods and cosmetics is
increasing owing to concerns about the rapid growth of the global population and climate …

Metabolic engineering for sustainability and health

GB Kim, SY Choi, IJ Cho, DH Ahn, SY Lee - Trends in Biotechnology, 2023 - cell.com
Bio-based production of chemicals and materials has attracted much attention due to the
urgent need to establish sustainability and enhance human health. Metabolic engineering …

[HTML][HTML] Targeted and high-throughput gene knockdown in diverse bacteria using synthetic sRNAs

JS Cho, D Yang, CPS Prabowo, MR Ghiffary… - Nature …, 2023 - nature.com
Synthetic sRNAs allow knockdown of target genes at translational level, but have been
restricted to a limited number of bacteria. Here, we report the development of a broad-host …

De novo biosynthesis of carminic acid in Saccharomyces cerevisiae

Q Zhang, X Wang, W Zeng, S Xu, D Li, S Yu… - Metabolic Engineering, 2023 - Elsevier
Carminic acid is a natural red dye extracted from the insect Dactylopius coccus. Due to its
ideal dying effect and high safety, it is widely used in food and cosmetics industries …

Precision fermentation for improving the quality, flavor, safety, and sustainability of foods

K Hilgendorf, Y Wang, MJ Miller, YS Jin - Current Opinion in Biotechnology, 2024 - Elsevier
Highlights•Precision fermentation can contribute to a sustainable future food
supply.•Genome-edited microorganisms can improve the qualities of fermented foods.•Food …

Production of natural pigments using microorganisms

Z Qin, X Wang, S Gao, D Li, J Zhou - Journal of Agricultural and …, 2023 - ACS Publications
Pigments are involved in many aspects of human life, including food, cosmetics, and textiles.
At present, the pigment market is mainly occupied by synthetic pigments. However, synthetic …

Strategies and extraction pathways towards carminic acid as natural-based food colorant: A comprehensive review

D Ferreyra-Suarez, L Paredes-Vargas, SM Jafari… - Advances in Colloid and …, 2023 - Elsevier
As a current trend of fabricating healthier products, food manufacturing companies seek for
natural-based food colorant aiming to replace the synthetic ones, which apart from meeting …

Metabolic and cellular engineering for the production of natural products

D Yang, H Eun, CPS Prabowo, S Cho… - Current Opinion in …, 2022 - Elsevier
Highlights•Systems metabolic engineering has enabled efficient production of natural
products.•Systems-level engineering of metabolism has increased pathway efficiencies.•Cell …

Methanotrophs as a reservoir for bioactive secondary metabolites: Pitfalls, insights and promises

UM Vasudevan, DHA Mai, S Krishna, EY Lee - Biotechnology Advances, 2023 - Elsevier
Methanotrophs are potent natural producers of several bioactive secondary metabolites
(SMs) including isoprenoids, polymers, peptides, and vitamins. Cryptic biosynthetic gene …