Lung cancer remains to be one of the most common and serious types of cancer worldwide.
While treatment is available, the survival rate of this cancer is still critically low due to late …

Lung cancer is considered the most deadly of all cancers, with limited therapeutic options.
Although advanced drugs have been tried in clinic, the therapeutic success has largely been …

Background Nanostructured lipid carriers (NLC), composed of solid and liquid lipids, and
surfactants are potentially good colloidal drug carriers. The aim of this study was to develop …

Exosomes are responsible for intercellular communication between tumor cells and others
in the tumor microenvironment. These microvesicles promote oncogensis and can support …

Previous studies have shown that microRNA-1304 (miR-1304) is dysregulated in certain
types of cancers, including non-small cell lung cancer (NSCLC), and might be involved in …

Inhibition or degradation of anti-apoptotic protein BCL-X L is a viable strategy for cancer
treatment. Despite the recent development of PROTACs for degradation of BCL-X L, the E3 …

Objective Hedgehog (HH) signaling has recently been associated with cartilage degradation
in osteoarthritis (OA). Because interleukin‐1β (IL‐1β) has been implicated as a principal …

Lung cancer is the most commonly diagnosed type of cancer and the leading cause of
cancer-associated death worldwide. MicroRNAs (miRNAs) are non-coding single-stranded …

Hepatocellular carcinoma (HCC) is the commonest primary liver cancer with highly
aggressive features. MicroRNAs (miRNAs) are demonstrated to play important roles in the …

MicroRNAs (miRNAs) are short non-coding RNAs that regulate genes posttranscriptionally.
Past studies have reported that miR-210 is up-regulated in many cancers including cervical …