Two severe, progressive neurological disorders characterized by intellectual disability,
autism, and developmental regression, Rett syndrome and MECP2 duplication syndrome …

Pontine respiratory nuclei provide synaptic input to medullary rhythmogenic circuits to shape
and adapt the breathing pattern. An understanding of this statement depends on …

In September of 2011, the National Institute of Neurological Disorders and Stroke (NINDS),
the Eunice Kennedy Shriver National Institute of Child Health and Human Development …

Rett syndrome (RTT) is an X-linked neurological disorder caused by mutations in the gene
encoding the transcriptional modulator methyl-CpG-binding protein 2 (MeCP2). Typical RTT …

Postnatal deficits in brain-derived neurotrophic factor (BDNF) are thought to contribute to
pathogenesis of Rett syndrome (RTT), a progressive neurodevelopmental disorder caused …

Excitatory-inhibitory imbalance has been identified within specific brain microcircuits in
models of Rett syndrome (RTT) and other autism spectrum disorders (ASDs). However …

Breathing disturbances are a major challenge in Rett Syndrome (RTT). These disturbances
are more pronounced during wakefulness; but irregular breathing occurs also during sleep …

Disorders of respiratory control are a prominent feature of Rett syndrome (RTT), a severely
debilitating condition caused by mutations in the gene encoding methyl-CpG-binding protein …

Serotonin (5-HT) is a neuromodulator–transmitter influencing global brain function. Past and
present findings illustrate a prominent role for 5-HT in the modulation of ponto-medullary …

Apnea of prematurity (AOP) is a significant clinical problem manifested by an unstable
respiratory rhythm reflecting the immaturity of respiratory control systems. This review will …