Mammalian heme peroxidases: from molecular mechanisms to health implications
A marked increase in interest has occurred over the last few years in the role that
mammalian heme peroxidase enzymes, primarily myeloperoxidase, eosinophil peroxidase …
mammalian heme peroxidase enzymes, primarily myeloperoxidase, eosinophil peroxidase …
Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons
T Shimada - Drug metabolism and pharmacokinetics, 2006 - jstage.jst.go.jp
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental carcinogens and
metabolized by a variety of xenobiotic-metabolizing enzymes such as cytochrome P450 …
metabolized by a variety of xenobiotic-metabolizing enzymes such as cytochrome P450 …
New microRNAs from mouse and human
M Lagos-Quintana, R Rauhut, J Meyer, A Borkhardt… - Rna, 2003 - rnajournal.cshlp.org
MicroRNAs (miRNAs) represent a new class of noncoding RNAs encoded in the genomes of
plants, invertebrates, and vertebrates. MicroRNAs regulate translation and stability of target …
plants, invertebrates, and vertebrates. MicroRNAs regulate translation and stability of target …
Inhalation exposure to ambient polycyclic aromatic hydrocarbons and lung cancer risk of Chinese population
An Euler atmospheric transport model (Canadian Model for Environmental Transport of
Organochlorine Pesticides, CanMETOP) was applied and validated to estimate polycyclic …
Organochlorine Pesticides, CanMETOP) was applied and validated to estimate polycyclic …
Oxidatively induced DNA damage: mechanisms, repair and disease
M Dizdaroglu - Cancer letters, 2012 - Elsevier
Endogenous and exogenous sources cause oxidatively induced DNA damage in living
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …
Epoxide hydrolases: their roles and interactions with lipid metabolism
JW Newman, C Morisseau, BD Hammock - Progress in lipid research, 2005 - Elsevier
The epoxide hydrolases (EHs) are enzymes present in all living organisms, which transform
epoxide containing lipids by the addition of water. In plants and animals, many of these lipid …
epoxide containing lipids by the addition of water. In plants and animals, many of these lipid …
Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles
C Morisseau, BD Hammock - Annu. Rev. Pharmacol. Toxicol., 2005 - annualreviews.org
▪ Abstract Organisms are exposed to epoxide-containing compounds from both exogenous
and endogenous sources. In mammals, the hydration of these compounds by various …
and endogenous sources. In mammals, the hydration of these compounds by various …
Mouse models for human lung cancer
R Meuwissen, A Berns - Genes & development, 2005 - genesdev.cshlp.org
In recent years several new mouse models for lung cancer have been described. These
include models for both non-small-cell lung cancer (NSCLC) and small-cell lung cancer …
include models for both non-small-cell lung cancer (NSCLC) and small-cell lung cancer …
[图书][B] An introductory philosophy of medicine: Humanizing modern medicine
JA Marcum - 2008 - books.google.com
In this book the author explores the shifting philosophical boundaries of modern medical
knowledge and practice occasioned by the crisis of quality-of-care, especially in terms of the …
knowledge and practice occasioned by the crisis of quality-of-care, especially in terms of the …
Sex differences in lung cancer susceptibility: a review
C Kiyohara, Y Ohno - Gender medicine, 2010 - Elsevier
Background: Several epidemiologic and molecular epidemiologic studies have indicated
that, for a given number of cigarettes smoked, women may be at higher risk of lung cancer …
that, for a given number of cigarettes smoked, women may be at higher risk of lung cancer …