Mammalian heme peroxidases: from molecular mechanisms to health implications

MJ Davies, CL Hawkins, DI Pattison… - Antioxidants & redox …, 2008 - liebertpub.com
A marked increase in interest has occurred over the last few years in the role that
mammalian heme peroxidase enzymes, primarily myeloperoxidase, eosinophil peroxidase …

Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons

T Shimada - Drug metabolism and pharmacokinetics, 2006 - jstage.jst.go.jp
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental carcinogens and
metabolized by a variety of xenobiotic-metabolizing enzymes such as cytochrome P450 …

New microRNAs from mouse and human

M Lagos-Quintana, R Rauhut, J Meyer, A Borkhardt… - Rna, 2003 - rnajournal.cshlp.org
MicroRNAs (miRNAs) represent a new class of noncoding RNAs encoded in the genomes of
plants, invertebrates, and vertebrates. MicroRNAs regulate translation and stability of target …

Inhalation exposure to ambient polycyclic aromatic hydrocarbons and lung cancer risk of Chinese population

Y Zhang, S Tao, H Shen, J Ma - Proceedings of the …, 2009 - National Acad Sciences
An Euler atmospheric transport model (Canadian Model for Environmental Transport of
Organochlorine Pesticides, CanMETOP) was applied and validated to estimate polycyclic …

Oxidatively induced DNA damage: mechanisms, repair and disease

M Dizdaroglu - Cancer letters, 2012 - Elsevier
Endogenous and exogenous sources cause oxidatively induced DNA damage in living
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …

Epoxide hydrolases: their roles and interactions with lipid metabolism

JW Newman, C Morisseau, BD Hammock - Progress in lipid research, 2005 - Elsevier
The epoxide hydrolases (EHs) are enzymes present in all living organisms, which transform
epoxide containing lipids by the addition of water. In plants and animals, many of these lipid …

Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles

C Morisseau, BD Hammock - Annu. Rev. Pharmacol. Toxicol., 2005 - annualreviews.org
▪ Abstract Organisms are exposed to epoxide-containing compounds from both exogenous
and endogenous sources. In mammals, the hydration of these compounds by various …

Mouse models for human lung cancer

R Meuwissen, A Berns - Genes & development, 2005 - genesdev.cshlp.org
In recent years several new mouse models for lung cancer have been described. These
include models for both non-small-cell lung cancer (NSCLC) and small-cell lung cancer …

[图书][B] An introductory philosophy of medicine: Humanizing modern medicine

JA Marcum - 2008 - books.google.com
In this book the author explores the shifting philosophical boundaries of modern medical
knowledge and practice occasioned by the crisis of quality-of-care, especially in terms of the …

Sex differences in lung cancer susceptibility: a review

C Kiyohara, Y Ohno - Gender medicine, 2010 - Elsevier
Background: Several epidemiologic and molecular epidemiologic studies have indicated
that, for a given number of cigarettes smoked, women may be at higher risk of lung cancer …