Matrix metalloproteinases (MMPs) are a family of zinc-dependent extracellular matrix (ECM)
remodeling endopeptidases that have the capacity to degrade almost every component of …

Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality. Reperfusion
strategies are the current standard therapy for AMI. However, they may result in paradoxical …

Cardiovascular disease is the leading cause of death, accounting for 600,000 deaths each
year in the United States. In addition, heart failure accounts for 37% of health care spending …

Quantitative assays for human DNA and mRNA were used to examine the paradox that
intravenously (iv) infused human multipotent stromal cells (hMSCs) can enhance tissue …

Kjær, Michael. Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to
Mechanical Loading. Physiol Rev 84: 649–698, 2004; 10.1152/physrev. 00031.2003.—The …

Early mechanical reperfusion of the epicardial coronary artery by primary percutaneous
coronary intervention (PCI) is the guideline-recommended treatment for ST-elevation …

Adverse cardiac remodeling following myocardial infarction (MI) remains a significant cause
of congestive heart failure. Additional and novel strategies that improve our ability to predict …

Myocardial infarction (MI) is one of the most common cardiac emergencies with high
morbidity and is a leading cause of death worldwide. Since MI could develop into a life …

Following myocardial infarction (MI), circulating blood monocytes respond to chemotactic
factors, migrate into the infarcted myocardium, and differentiate into macrophages. At the …

Wounding and healing are archaic principles, prerequisite for survival of any biologic
material. However, strategies to cope with wounding may be quite different among …