Mechanistic and therapeutic relationships of traumatic brain injury and γ-amino-butyric acid (GABA)
JM Witkin, H Shafique, JL Smith, AM Marini… - Pharmacology & …, 2024 - Elsevier
Traumatic brain injury is a highly prevalent medical condition for which no medications
specific for the prophylaxis or treatment of the condition as a whole exist. The spectrum of …
specific for the prophylaxis or treatment of the condition as a whole exist. The spectrum of …
[HTML][HTML] Metabolite changes and impact factors in mild traumatic brain injury patients: a review on magnetic resonance spectroscopy
The high incidence of mild traumatic brain injury (mTBI) and the associated post-concussion
symptoms, such as headache and cognitive deficits, have captured the significant attention …
symptoms, such as headache and cognitive deficits, have captured the significant attention …
[HTML][HTML] Prefrontal Glutathione Levels in Major Depressive Disorder Are Linked to a Lack of Positive Affect
ROG Tuura, A Buchmann, C Ritter, A Hase, M Haynes… - Brain Sciences, 2023 - mdpi.com
Major depressive disorder (MDD) is one of the most common neuropsychiatric disorders,
with symptoms including persistent sadness and loss of interest. MDD is associated with …
with symptoms including persistent sadness and loss of interest. MDD is associated with …
[HTML][HTML] Exploring brain glutathione and peripheral blood markers in posttraumatic stress disorder: a combined [1H] MRS and peripheral blood study
Introduction Oxidative stress has been implicated in psychiatric disorders, including
posttraumatic stress disorder (PTSD). Currently, the status of glutathione (GSH), the brain's …
posttraumatic stress disorder (PTSD). Currently, the status of glutathione (GSH), the brain's …
[HTML][HTML] Poor nutritional status is associated with incomplete functional recovery in elderly patients with mild traumatic brain injury
B Zhu, Y Ou, X Guo, W Liu, L Wu - Frontiers in Neurology, 2023 - frontiersin.org
Background The geriatric nutritional risk index (GNRI) is a simple index for evaluating the
nutrition status of elderly patients. Many investigations have demonstrated that this index is …
nutrition status of elderly patients. Many investigations have demonstrated that this index is …
[HTML][HTML] Effects of isoflurane and urethane anesthetics on glutamate neurotransmission in rat brain using in vivo amperometry
Background Aspects of glutamate neurotransmission implicated in normal and pathological
conditions are predominantly evaluated using in vivo recording paradigms in rats …
conditions are predominantly evaluated using in vivo recording paradigms in rats …
[HTML][HTML] Evaluating Back-to-Back and Day-to-Day Reproducibility of Cortical GABA+ Measurements Using Proton Magnetic Resonance Spectroscopy (1H MRS)
γ-aminobutyric acid (GABA) is a major inhibitory neurotransmitter implicated in
neuropsychiatric disorders. The best method for quantifying GABA is proton magnetic …
neuropsychiatric disorders. The best method for quantifying GABA is proton magnetic …
Visualizing Posttraumatic stress disorder with in vivo brain imaging: a multimodal approach
SE Watling - 2023 - search.proquest.com
Our limited understanding of biological mechanisms underpinning Posttraumatic Stress
Disorder (PTSD) is preventing effective drug development. Inflammation and oxidative stress …
Disorder (PTSD) is preventing effective drug development. Inflammation and oxidative stress …